Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Despite great successes in oncology, patient outcomes are often still discouraging, and
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …

In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Signal amplification by reversible exchange (SABRE) turns typically weak magnetic
resonance responses into strong signals making previously impractical measurements …

This review summarises the most recent advances in Ir–NHC catalysis while revisiting all the
classical reactions in which this type of catalyst has proved to be active. The influence of the …

Signal Amplification by Reversible Exchange (SABRE) is a fast and convenient NMR
hyperpolarization method that uses cheap and readily available para-hydrogen as a …

Direct NMR hyperpolarization of naturally abundant 15N sites in metronidazole is
demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in …

α-Ketoglutarate is a key biomolecule involved in a number of metabolic pathways─ most
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with …