Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials

M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022 - ASPET
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Effect of particulate matter-bound metals exposure on prothrombotic biomarkers: a systematic review

S Santo Signorelli, GO Conti, A Zanobetti… - Environmental …, 2019 - Elsevier
Environmental pollution is an important modifiable determinant for preventing
cardiovascular diseases. Acute exposure to air pollution is linked to severe adverse …

Mortality and morbidity due to exposure to outdoor air pollution in Mashhad metropolis, Iran. The AirQ model approach

M Miri, Z Derakhshan, A Allahabadi, E Ahmadi… - Environmental …, 2016 - Elsevier
In the past two decades, epidemiological studies have shown that air pollution is one of the
causes of morbidity and mortality. In this study the effect of PM10, PM2. 5, NO2, SO2 and O3 …

Carnitine derivatives: clinical usefulness

M Malaguarnera - Current opinion in gastroenterology, 2012 - journals.lww.com
Carnitine derivatives: clinical usefulness : Current Opinion in Gastroenterology Carnitine
derivatives: clinical usefulness : Current Opinion in Gastroenterology Log in or Register …

[HTML][HTML] L-Carnitine supplementation for adults with end-stage kidney disease requiring maintenance hemodialysis: a systematic review and meta-analysis

Y Chen, M Abbate, L Tang, G Cai, Z Gong… - The American journal of …, 2014 - Elsevier
Background: A previous meta-analysis indicated that l-carnitine significantly increased
hemoglobin and decreased the required erythropoietin dose in maintenance hemodialysis …

The role of L-carnitine in kidney disease and related metabolic dysfunctions

T Ulinski, M Cirulli, MA Virmani - Kidney and Dialysis, 2023 - mdpi.com
Kidney disease is associated with a wide variety of metabolic abnormalities that accompany
the uremic state and the state of dialysis dependence. These include altered L-carnitine …

Predictive modelling of nitrogen dioxide using soft computing techniques in the Agra, Uttar Pradesh, India

P Sihag, T Mehta, SS Sammen, CB Pande… - … of the Earth, Parts A/B/C, 2024 - Elsevier
Nitrogen dioxide (NO 2) is one of the air pollutants which aggravates the human health as
well as causes environmental issues. It is more causes respiratory problems due to acid …

Pharmacological effects and clinical applications of propionyl-L-carnitine

C Mingorance, R Rodriguez-Rodriguez… - Nutrition …, 2011 - academic.oup.com
Abstract Propionyl-L-carnitine (PLC) is a naturally occurring derivative of carnitine that plays
an important role in the metabolism of both carbohydrates and lipids, leading to an increase …

Oxidative stress and inflammation: their role in the pathogenesis of peripheral artery disease with or without type 2 diabetes mellitus

SS Signorelli, N Katsiki - Current vascular pharmacology, 2018 - ingentaconnect.com
Peripheral Artery Disease (PAD), a common vascular disease, has been associated with
increased Cardiovascular (CV) morbidity and mortality as well as all-cause death. Type 2 …

Interventions for lowering plasma homocysteine levels in dialysis patients

SU Nigwekar, A Kang, S Zoungas… - Cochrane Database …, 2016 - cochranelibrary.com
Background People with end‐stage kidney disease (ESKD) have high rates of
cardiovascular events. Randomised controlled trials (RCTs) of homocysteine‐lowering …