Neuromyelitis optica and multiple sclerosis: seeing differences through optical coherence tomography

JL Bennett, J de Seze, M Lana-Peixoto… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous
system that preferentially targets the optic nerves and spinal cord. The clinical presentation …

Aquaporin-4 autoimmunity

A Zekeridou, VA Lennon - Neuroimmunology & Neuroinflammation, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) and a related spectrum of inflammatory CNS disorders are
unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water …

Pathogenic autoantibodies in multiple sclerosis—from a simple idea to a complex concept

R Höftberger, H Lassmann, T Berger… - Nature Reviews …, 2022 - nature.com
The role of autoantibodies in multiple sclerosis (MS) has been enigmatic since the first
description, many decades ago, of intrathecal immunoglobulin production in people with this …

[HTML][HTML] The immunology of neuromyelitis optica—current knowledge, clinical implications, controversies and future perspectives

M Jasiak-Zatonska, A Kalinowska-Lyszczarz… - International journal of …, 2016 - mdpi.com
Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central
nervous system (CNS) with typical clinical manifestations of optic neuritis and acute …

B cells in MS and NMO: pathogenesis and therapy

M Krumbholz, E Meinl - Seminars in immunopathology, 2014 - Springer
B linage cells are versatile players in multiple sclerosis (MS) and neuromyelitis
optica/neuromyelitis optica spectrum disorder (NMO). New potential targets of …

Epidemiological, clinical, and immunological characteristics of neuromyelitis optica: a review

WLCJ Pereira, EMV Reiche, AP Kallaur… - Journal of the …, 2015 - Elsevier
The aim of this study was to review the epidemiological and clinical characteristics of
neuromyelitis optica (NMO) and the immunopathological mechanisms involved in the …

Recent advances in the understanding of the pathophysiology of neuromyelitis optica spectrum disorder

VTW Chang, HM Chang - Neuropathology and applied …, 2020 - Wiley Online Library
Neuromyelitis optica is an autoimmune inflammatory disorder of the central nervous system
that preferentially targets the spinal cord and optic nerve. Following the discovery of …

[HTML][HTML] Involvement of aquaporins in the pathogenesis, diagnosis and treatment of Sjögren's syndrome

MS Soyfoo, C Chivasso, J Perret… - International journal of …, 2018 - mdpi.com
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic
infiltration of salivary and lacrimal glands resulting in diminished production of saliva and …

Autoimmune AQP4 channelopathies and neuromyelitis optica spectrum disorders

SR Hinson, VA Lennon, SJ Pittock - Handbook of clinical neurology, 2016 - Elsevier
Neuromyelitis optica (NMO) spectrum disorders (SD) represent an evolving group of central
nervous system (CNS)-inflammatory autoimmune demyelinating diseases unified by a …

[HTML][HTML] Aquaporins in the spinal cord

MK Oklinski, MT Skowronski, A Skowronska… - International journal of …, 2016 - mdpi.com
Aquaporins (AQPs) are water channel proteins robustly expressed in the central nervous
system (CNS). A number of previous studies described the cellular expression sites and …