miRNA targets: from prediction tools to experimental validation

G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …

The role of M6A modification in the regulation of tumor-related lncRNAs

Y Lan, B Liu, H Guo - Molecular Therapy-Nucleic Acids, 2021 - cell.com
N 6-methyladenosine (m 6 A) is the most abundant modification in eukaryotic cells, and it
regulates RNA transcription, processing, splicing, degradation, and translation. Long non …

In silico discovery of candidate drugs against Covid-19

C Cava, G Bertoli, I Castiglioni - Viruses, 2020 - mdpi.com
Previous studies reported that Angiotensin converting enzyme 2 (ACE2) is the main cell
receptor of SARS-CoV and SARS-CoV-2. It plays a key role in the access of the virus into the …

Long noncoding RNA ZFAS1 promoting small nucleolar RNA-mediated 2′-O-methylation via NOP58 recruitment in colorectal cancer

H Wu, W Qin, S Lu, X Wang, J Zhang, T Sun, X Hu… - Molecular Cancer, 2020 - Springer
Background Increasing evidence supports the role of small nucleolar RNAs (snoRNAs) and
long non-coding RNAs (lncRNAs) as master gene regulators at the epigenetic modification …

[HTML][HTML] The crucial role of non-coding RNAs in the pathophysiology of inflammatory bowel disease

S Ghafouri-Fard, R Eghtedarian, M Taheri - Biomedicine & …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is chronic inflammatory disorder of the gastrointestinal
(GI) tract which pose significant social and economic burden on health system. Crohn's …

Identification of long non-coding RNAs and RNA binding proteins in breast cancer subtypes

C Cava, A Armaos, B Lang, GG Tartaglia… - Scientific Reports, 2022 - nature.com
Breast cancer is a heterogeneous disease classified into four main subtypes with different
clinical outcomes, such as patient survival, prognosis, and relapse. Current genetic tests for …

In silico identification of miRNA–lncRNA interactions in male reproductive disorder associated with COVID-19 infection

S Sabetian, I Castiglioni, BN Jahromi, P Mousavi… - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), a global pandemic, is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 …

Integrated analysis of lncRNA–miRNA–mRNA ceRNA network and the potential prognosis indicators in sarcomas

L Gao, Y Zhao, X Ma, L Zhang - BMC Medical Genomics, 2021 - Springer
Abstract Background Competitive endogenous RNA (ceRNA) networks have revealed a
new mechanism of interaction between RNAs, and play crucial roles in multiple biological …

Systematic analysis of inheritance pattern determination in genes that cause rare neurodevelopmental diseases

S Park, SS Jang, S Lee, M Kim, H Sim, H Jeon… - Frontiers in …, 2022 - frontiersin.org
Despite recent advancements in our understanding of genetic etiology and its molecular and
physiological consequences, it is not yet clear what genetic features determine the …

Long noncoding rnas that function in nutrition: lnc-ing nutritional cues to metabolic pathways

CD Lovell, MC Anguera - Annual Review of Nutrition, 2022 - annualreviews.org
Long noncoding RNAs (lncRNAs) are sensitive to changing environments and play key
roles in health and disease. Emerging evidence indicates that lncRNAs regulate gene …