Redox biology of tuberculosis pathogenesis
Mycobacterium tuberculosis (Mtb) is one of the most successful human pathogens. Mtb is
persistently exposed to numerous oxidoreductive stresses during its pathogenic cycle of …
persistently exposed to numerous oxidoreductive stresses during its pathogenic cycle of …
Truncated (2/2) hemoglobin: Unconventional structures and functional roles in vivo and in human pathogenesis
Truncated hemoglobins (trHbs) build a sub-class of the globin family, found in eubacteria,
cyanobacteria, unicellular eukaryotes, and in higher plants; among these, selected human …
cyanobacteria, unicellular eukaryotes, and in higher plants; among these, selected human …
Evolutionary origin and ecological implication of a unique nif island in free-living Bradyrhizobium lineages
The alphaproteobacterial genus Bradyrhizobium has been best known as N2-fixing
members that nodulate legumes, supported by the nif and nod gene clusters. Recent …
members that nodulate legumes, supported by the nif and nod gene clusters. Recent …
The diversity of 2/2 (truncated) globins
Small size globins that have been defined as 'truncated haemoglobins' or as '2/2
haemoglobins' have increasingly been discovered in microorganisms since the early 1990s …
haemoglobins' have increasingly been discovered in microorganisms since the early 1990s …
[HTML][HTML] Upregulation and mitochondrial sequestration of hemoglobin occur in circulating leukocytes during critical illness, conferring a cytoprotective phenotype
The classical role of hemoglobin in the erythrocytes is to carry oxygen from the lungs to the
tissues via the circulation. However, hemoglobin also acts as a redox regulator and as a …
tissues via the circulation. However, hemoglobin also acts as a redox regulator and as a …
The role of a 2-on-2 haemoglobin in oxidative and nitrosative stress resistance of Antarctic Pseudoalteromonas haloplanktis TAC125
The 2-on-2 haemoglobins, previously named truncated, are monomeric, low-molecular
weight oxygen-binding proteins that share the overall topology with vertebrate …
weight oxygen-binding proteins that share the overall topology with vertebrate …
Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins
E De Marinis, L Casella, C Ciaccio, M Coletta… - IUBMB …, 2009 - Wiley Online Library
Globins are generally considered as carriers of diatomic gaseous ligands (eg, O2 and NO)
in metazoa. Recently, the (pseudo‐) enzymatic activity of globins towards reactive nitrogen …
in metazoa. Recently, the (pseudo‐) enzymatic activity of globins towards reactive nitrogen …
Transcript analysis and expression of the glbO gene, encoding truncated hemoglobin, O, of M. Smegmatis implicate its role under hypoxia and oxidative stress
Although truncated hemoglobin O,(trHbO), is ubiquitous among mycobacteria, its
physiological function is not very obvious and may be diverse. In an attempt to understand …
physiological function is not very obvious and may be diverse. In an attempt to understand …
Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations
Ultraviolet radiation, an effective sterilizing source, rapidly kills the causative organism
(Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly …
(Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly …
The globins of cold-adapted Pseudoalteromonas haloplanktis TAC125: from the structure to the physiological functions
Evolution allowed Antarctic microorganisms to grow successfully under extreme conditions
(low temperature and high O 2 content), through a variety of structural and physiological …
(low temperature and high O 2 content), through a variety of structural and physiological …