Chiral hydroxylamines are increasingly common structural elements in pharmaceuticals and
agrochemicals, but their asymmetric synthesis remains challenging. Although …

Poly (disulfide) s are an emerging class of sulfur-containing polymers with applications in
medicine, energy, and functional materials. However, the constituent dynamic covalent S–S …

Catalytic asymmetric preparation of chiral 3-monosubstituted oxindoles represents a
significant challenge in synthetic chemistry due to the ease of racemization of the tertiary …

A systematic study of the entropic penalty for associative reactions is presented. It is shown
that computed solution-phase Gibbs free energies typically overestimate entropic …

Chiral N-alkoxy amines are increasingly vital substrates in bioscience. However, asymmetric
synthetic strategies for these compounds remain scarce. Catalytic kinetic resolution …

Mesoionic compounds are the starting material for the synthesis of unique anionic N-
heterocyclic carbenes. Herein, mesoionic imidazolium pyrrolides synthesized from pyrrole-2 …

Herein we report a density functional theory (DFT)-guided mechanistic investigation of the
nitrile reduction reaction, which exhibits a solvent-dependent chemodivergence. This study …

The use of boronic acids as additives in synthesis and catalysis has been gaining attention
in recent years. This chapter is aimed at highlighting the characteristics of boronic acids that …