[HTML][HTML] Current applications and different approaches for microbial L-asparaginase production

JJM Cachumba, FAF Antunes, GFD Peres… - Brazilian journal of …, 2016 - SciELO Brasil
ABSTRACT L-asparaginase (EC 3.5. 1.1) is an enzyme that catalysis mainly the asparagine
hydrolysis in L-aspartic acid and ammonium. This enzyme is presented in different …

[HTML][HTML] Marine microbial L-asparaginase: biochemistry, molecular approaches and applications in tumor therapy and in food industry

FI Qeshmi, A Homaei, P Fernandes… - Microbiological Research, 2018 - Elsevier
The marine environment is a rich source of biological and chemical diversity. It covers more
than 70% of the Earth's surface and features a wide diversity of habitats, often displaying …

Production and Anticancer Activity of an L-Asparaginase from Bacillus licheniformis Isolated from the Red Sea, Saudi Arabia

SA Alrumman, YS Mostafa, KA Al-Izran, MY Alfaifi… - Scientific reports, 2019 - nature.com
Microbial L-asparaginase (ASNase) is an important anticancer agent that is used
extensively worldwide. In this study, 40 bacterial isolates were obtained from the Red Sea of …

Production of a Novel Marine Pseudomonas aeruginosa Recombinant L-Asparaginase: Insight on the Structure and Biochemical Characterization

F Izadpanah Qeshmi, A Homaei, K Khajeh… - Marine …, 2022 - Springer
The present study focused on the cloning, expression, and characterization of L-
asparaginase of marine Pseudomonas aeruginosa HR03 isolated from fish intestine. Thus …

Marine enzymes: Classification and application in various industries

S Ghattavi, A Homaei - International Journal of Biological Macromolecules, 2023 - Elsevier
Oceans are regarded as a plentiful and sustainable source of biological compounds.
Enzymes are a group of marine biomaterials that have recently drawn more attention …

Fungal biosynthesis of lignin-modifying enzymes from pulp wash and Luffa cylindrica for azo dye RB5 biodecolorization using modeling by response surface …

CD Fernandes, VRS Nascimento, DB Meneses… - Journal of hazardous …, 2020 - Elsevier
This study demonstrates the evaluation between the artificial neural network technique
coupled to the genetic algorithm (ANN-GA) and the response surface methodology (RSM) …

[HTML][HTML] Enzyme–polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms

S Khan, MMN Babadaei, A Hasan, Z Edis… - Journal of Advanced …, 2021 - Elsevier
Background Because enzymes can control several metabolic pathways and regulate the
production of free radicals, their simultaneous use with nanoplatforms showing protective …

[HTML][HTML] Thermostable Chitosan-L-Asparaginase conjugate from Aspergillus fumigatus is a novel structurally stable composite for abolishing acrylamide formation in …

MA Yassin, A Shindia, M Labib, M Soud, ASA El-Sayed - Lwt, 2022 - Elsevier
Abstract l-Asparaginase (Asnase) is one of the most promising approaches for acrylamide
mitigation in foods, however, the enzyme stability and catalytic efficiency are the major …

Exploring current scenario and developments in the field of microbial L-asparaginase production and applications: A review

PG Patel, HZ Panseriya, AK Vala, BP Dave… - Process …, 2022 - Elsevier
L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …

[HTML][HTML] Enhanced production of glutaminase-free L-asparaginase by marine Bacillus velezensis and cytotoxic activity against breast cancer cell lines

Y Mostafa, S Alrumman, S Alamri, M Hashem… - Electronic Journal of …, 2019 - Elsevier
Background The increasing rate of breast cancer globally requires extraordinary efforts to
discover new effective sources of chemotherapy with fewer side effects. Glutaminase-free l …