Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update 2018

AF Peery, SD Crockett, CC Murphy, JL Lund, ES Dellon… - Gastroenterology, 2019 - Elsevier
Background & Aims Estimates of disease burden can inform national health priorities for
research, clinical care, and policy. We aimed to estimate health care use and spending …

Early-onset colorectal cancer: initial clues and current views

LJ Hofseth, JR Hebert, A Chanda, H Chen… - Nature reviews …, 2020 - nature.com
Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

Dysbiosis of human gut microbiome in young-onset colorectal cancer

Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …

Epidemiology and mechanisms of the increasing incidence of colon and rectal cancers in young adults

EM Stoffel, CC Murphy - Gastroenterology, 2020 - Elsevier
In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …

Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women

J Hur, E Otegbeye, HK Joh, K Nimptsch, K Ng, S Ogino… - Gut, 2021 - gut.bmj.com
Objective Sugar-sweetened beverage (SSB) consumption had substantially increased
across successive US birth cohorts until 2000, and adolescents and young adults under age …

Colorectal cancer: preoperative evaluation and staging

NN Mahmoud - Surgical Oncology Clinics, 2022 - surgonc.theclinics.com
Colorectal cancer is a widespread clinical entity—affecting more than 1 million individuals
globally on an annual basis. 1–3 Colorectal cancer remains the third most common nonskin …

Recent trends in the incidence and survival of stage 1A pancreatic cancer: a surveillance, epidemiology, and end results analysis

AL Blackford, MI Canto, AP Klein… - JNCI: Journal of the …, 2020 - academic.oup.com
Background Rapid access to pancreatic imaging and regular pancreatic surveillance may
help identify stage I pancreatic cancer. We investigated recent trends in the stage of newly …

Cumulative burden of colorectal cancer–associated genetic variants is more strongly associated with early-onset vs late-onset cancer

AN Archambault, YR Su, J Jeon, M Thomas, Y Lin… - Gastroenterology, 2020 - Elsevier
Background & Aims Early-onset colorectal cancer (CRC, in persons younger than 50 years
old) is increasing in incidence; yet, in the absence of a family history of CRC, this population …

[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or
women in the United States. Average-risk screening that begins at age 50 years has …

[HTML][HTML] Young-onset colorectal cancer: A review

JZ Done, SH Fang - World journal of gastrointestinal oncology, 2021 - ncbi.nlm.nih.gov
Despite the general decrease in overall incidence of colorectal cancer since the early
1990s, the incidence of colorectal cancer in patients less than 50 years old has nearly …