Clinical management of congenital hypogonadotropic hypogonadism

J Young, C Xu, GE Papadakis, JS Acierno… - Endocrine …, 2019 - academic.oup.com
The initiation and maintenance of reproductive capacity in humans is dependent on pulsatile
secretion of the hypothalamic hormone GnRH. Congenital hypogonadotropic hypogonadism …

The role of androgen and its related signals in PCOS

W Ye, T Xie, Y Song, L Zhou - Journal of cellular and molecular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women at
reproductive age. However, the underlying pathogenic mechanisms have not been …

Beyond the X factor: relevance of sex hormones in NAFLD pathophysiology

S Della Torre - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being
frequently associated with obesity, unbalanced dietary regimens, and reduced physical …

Change in visceral fat and total body fat and the effect on cardiometabolic risk factors during transgender hormone therapy

M Klaver, D van Velzen, C de Blok… - The Journal of …, 2022 - academic.oup.com
Introduction Excess visceral fat increases the risk of type 2 diabetes and cardiovascular
disease and is influenced by sex hormones. Our aim was to investigate changes in visceral …

Diagnosis and treatment of testosterone deficiency: updated recommendations from the Lisbon 2018 International Consultation for Sexual Medicine

A Morgentaler, A Traish, G Hackett… - Sexual medicine …, 2019 - academic.oup.com
Abstract Introduction The International Consultation for Sexual Medicine met in Lisbon in
2018 to review updated recommendations regarding testosterone deficiency (TD) and its …

Testosterone level and risk of type 2 diabetes in men: a systematic review and meta-analysis

Q Yao, B Wang, X An, J Zhang… - Endocrine …, 2018 - ec.bioscientifica.com
Background Type 2 diabetes is a risk factor for testosterone deficiency and impaired sex
steroid status. Some studies also investigated the association of testosterone level with …

Randomized controlled trials–mechanistic studies of testosterone and the cardiovascular system

TH Jones, DM Kelly - Asian journal of andrology, 2018 - journals.lww.com
Testosterone deficiency is common in men with cardiovascular disease (CVD), and
randomized placebo-controlled trials (RCTs) have reported beneficial effects of testosterone …

Hormonal treatment and cardiovascular risk profile in transgender adolescents

M Klaver, R de Mutsert, MATC van der Loos… - …, 2020 - publications.aap.org
METHODS: Changes in BMI, systolic blood pressure (SBP), diastolic blood pressure (DBP),
glucose, homeostatic model assessment for insulin resistance (HOMA-IR), and lipid values …

[HTML][HTML] An overview on androgen-mediated actions in skeletal muscle and adipose tissue

J Rizk, R Sahu, D Duteil - Steroids, 2023 - Elsevier
Androgens are a class of steroid hormones primarily associated with male sexual
development and physiology, but exert pleiotropic effects in either sex. They have a crucial …

Insight into potential interactions of thyroid hormones, sex hormones and their stimulating hormones in the development of non-alcoholic fatty liver disease

E Fröhlich, R Wahl - Metabolites, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is a common manifestation of metabolic
syndrome. In addition to lifestyle, endocrine hormones play a role in the dysregulation of …