Эффекты тиреоидных гормонов в развитии нервной системы (обзор)

ДБ Дёмин - Журнал медико-биологических исследований, 2018 - cyberleninka.ru
Гипоталамо-гипофизарно-тиреоидная система играет важную роль не только в
регуляции развивающейся нервной системы ребенка, но и в функционировании …

The cross-sectional and longitudinal association between thyroid function and depression: a population-based study

OH Roa Dueñas, A Hofman, AI Luik… - The Journal of …, 2024 - academic.oup.com
Context An association of thyroid function with mood disorders has been widely suggested,
but very few studies have examined this association longitudinally. Objective We assessed …

MEGA‐PRESS of GABA+: influences of acquisition parameters

DK Deelchand, M Marjańska, PG Henry… - NMR in …, 2021 - Wiley Online Library
γ‐aminobutyric acid (GABA) was the first molecule that was edited with MEGA‐PRESS.
GABA edited spectroscopy is challenged by limited selectivity of editing pulses. Coediting of …

Association of altered thyroid hormones and neurometabolism to cognitive dysfunction in unmedicated bipolar II depression

S Lai, S Zhong, Y Zhang, Y Wang, H Zhao… - Progress in Neuro …, 2021 - Elsevier
Background The underlying mechanism of cognitive impairment in bipolar II depression (BD
II) remains unclear. Studies show disturbances of the hypothalamus-pituitary-thyroid (HPT) …

Inhibitory motor dysfunction in parkinson's disease subtypes

T Gong, Y Xiang, MG Saleh, F Gao… - Journal of Magnetic …, 2018 - Wiley Online Library
Background Parkinson's disease (PD) is divided into postural instability gait difficulty (PIGD)
and tremor‐dominant (TD) subtypes. Increasing evidence has suggested that the GABAergic …

Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder

AJ Johnson, E Shankland, T Richards… - Psychiatry Research …, 2023 - Elsevier
Theories of altered inhibitory/excitatory signaling in autism spectrum disorder (ASD) suggest
that gamma amino butyric acid (GABA) and glutamate (Glu) abnormalities may underlie …

Deficiency of Thyroid Hormone Reduces Voltage-Gated Na+ Currents as Well as Expression of Na+/K+-ATPase in the Mouse Hippocampus

SM Sundaram, R Marx, HM Lesslich… - International Journal of …, 2022 - mdpi.com
Mice lacking functional thyroid follicular cells, Pax8−/− mice, die early postnatally, making
them suitable models for extreme hypothyroidism. We have previously obtained evidence in …

Neurometabolite and cognitive changes in hypothyroid patients in response to treatment: In-vivo 1H MRS Study

M Kumar, S Singh, P Rana, M D'souza… - Neurochemistry …, 2024 - Elsevier
The disturbances in thyroid hormones lead to altered brain metabolism, function, and
cognition. Neuroimaging studies have shown structural and functional changes in …

[HTML][HTML] Brain GABA+ changes in primary hypothyroidism patients before and after levothyroxine treatment: A longitudinal magnetic resonance spectroscopy study

B Liu, Z Wang, L Lin, H Yang, F Gao, T Gong… - NeuroImage: Clinical, 2020 - Elsevier
Objective Increasing evidence indicates the involvement of the GABAergic system in the
pathophysiology of hypothyroidism. We aimed to investigate longitudinal changes of brain …

Feasibility of measuring GABA levels in the upper brainstem in healthy volunteers using edited MRS

Y Song, T Gong, RAE Edden, G Wang - Frontiers in Psychiatry, 2020 - frontiersin.org
Purpose To assess the feasibility of small-voxel MEGA-PRESS in detecting gamma-
aminobutyric acid (GABA) levels of the upper brainstem in healthy volunteers. Materials and …