Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

Basophils have been recognized as important players for protective immunity against a
variety of different endo-and ectoparasites. Although basophils represent a relatively rare …

Being discovered long ago basophils have been neglected for more than a century. During
the past decade evidence emerged that basophils share features of innate and adaptive …

Genetic mapping and genome-wide studies provide evidence for the association of several
genetic polymorphisms with malaria, a complex pathological disease with multiple severity …

Genetic mapping has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …

Malaria is a common and sometimes fatal disease caused by infection with Plasmodium
parasites. Cerebral malaria (CM) is a most severe complication of infection with Plasmodium …

Infectious diseases are responsible for over 25% of deaths globally, but many more
individuals are exposed to deadly pathogens. The outcome of infection results from a set of …

Malaria remains a deadly parasitic disease caused by Plasmodium, claiming almost half a
million lives every year. While parasite genetics and biology are often the major targets in …

Forward genetic approaches have been widely used in parasitology and have proven their
power to reveal the complexities of host-parasite interactions in an unbiased fashion. Many …

Background There is an urgent need to develop and test novel compounds against malaria
infection. Carrageenans, sulphated polysaccharides derived from seaweeds, have been …