Current drug therapy and pharmaceutical challenges for Chagas disease
One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …
The use of animal models in homeopathic research–a review of 2010–2014 PubMed indexed papers
LV Bonamin, TN Cardoso, AC de Carvalho… - …, 2015 - thieme-connect.com
Background: In the 1990s, a study was performed on the effects of highly diluted thyroxine
on frog metamorphosis. This model represented one of the most discussed examples of the …
on frog metamorphosis. This model represented one of the most discussed examples of the …
Immune and antioxidant enzyme response of Longfin yellowtail (Seriola rivoliana) juveniles to ultra-diluted substances derived from phosphorus, silica and …
Background This research aimed to observe the effect of homeopathic treatments prepared
from Vibrio parahaemolyticus and V. alginolyticus (H1) and commercial homeopathic …
from Vibrio parahaemolyticus and V. alginolyticus (H1) and commercial homeopathic …
Modulation of inflammation response to murine cutaneous Leishmaniasis by homeopathic medicines: Antimonium crudum 30cH
FR de Santana, C de Paula Coelho, TN Cardoso… - …, 2014 - thieme-connect.com
Background: Leishmaniasis is a zoonotic disease caused by protozoan parasites of the
mononuclear phagocytic system. The modulation activity of these cells can interfere in the …
mononuclear phagocytic system. The modulation activity of these cells can interfere in the …
[HTML][HTML] Could phenothiazine-benznidazole combined chemotherapy be effective in controlling heart parasitism and acute infectious myocarditis?
AAS Mendonça, E Gonçalves-Santos… - Pharmacological …, 2020 - Elsevier
Phenothiazines inhibit major antioxidant defense mechanisms in trypanosomatids and
exhibit potent cytotoxic effects in vitro. However, the relevance of these drugs in the …
exhibit potent cytotoxic effects in vitro. However, the relevance of these drugs in the …
New Drugs and Promising Drug Combinations in the Treatment of Chagas Disease in Brazil: A Systematic Review and Meta-Analysis
ES Freire, LP da Silva, A do Carmo Silva… - Archives of Medical …, 2025 - Elsevier
Chagas disease (CD) is a parasitic infection caused by the protozoan Trypanosoma cruzi
(Kinetoplastida, Trypanosomatidae). Benznidazole (Bz) has a limited ability to interfere with …
(Kinetoplastida, Trypanosomatidae). Benznidazole (Bz) has a limited ability to interfere with …
Highly diluted medication reduces tissue parasitism and inflammation in mice infected by Trypanosoma cruzi
CR Lopes, GJS Falkowski, CF Brustolin… - …, 2016 - thieme-connect.com
Aim: To evaluate the effects of Kalium causticum, Conium maculatum, and Lycopodium
clavatum 13cH in mice infected by Trypanosoma cruzi. Materials and methods: In a blind …
clavatum 13cH in mice infected by Trypanosoma cruzi. Materials and methods: In a blind …
[HTML][HTML] Thioridazine aggravates skeletal myositis, systemic and liver inflammation in Trypanosoma cruzi-infected and benznidazole-treated mice
AAS Mendonca, E Goncalves-Santos… - International …, 2020 - Elsevier
While thioridazine (Tio) inhibits the antioxidant defenses of Trypanosoma cruzi, the gold
standard antitrypanosomal drug benznidazole (Bz) has potent anti-inflammatory and pro …
standard antitrypanosomal drug benznidazole (Bz) has potent anti-inflammatory and pro …
Trypanosoma cruzi: biotherapy made from trypomastigote modulates the inflammatory response
P Sandri, DL Aleixo, GJS Falkowski, ADN Júnior… - …, 2015 - thieme-connect.com
This study evaluates the effect of Trypanosoma cruzi biotherapy 17dH (BIOT) on mice of
different ages, infected with the protozoa concerned. Method: Performing a blind, controlled …
different ages, infected with the protozoa concerned. Method: Performing a blind, controlled …
The use of a heterogeneously controlled mouse population reveals a significant correlation of acute phase parasitemia with mortality in Chagas disease
Chagas disease develops upon infection with the protozoan parasite Trypanosoma cruzi
and undergoes an acute phase characterized by massive parasite replication and the …
and undergoes an acute phase characterized by massive parasite replication and the …