Principles and applications of nucleic acid strand displacement reactions
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
Isothermal nucleic acid amplification technology for rapid detection of virus
While the research field and industrial market of in vitro diagnosis (IVD) thrived during and
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …
post the COVID-19 pandemic, the development of isothermal nucleic acid amplification test …
Toehold-mediated strand displacement in random sequence pools
Toehold-mediated strand displacement (TMSD) has been used extensively for molecular
sensing and computing in DNA-based molecular circuits. As these circuits grow in …
sensing and computing in DNA-based molecular circuits. As these circuits grow in …
DNA Strand Displacement Driven by Host–Guest Interactions
DVDW Kankanamalage, JHT Tran… - Journal of the …, 2022 - ACS Publications
Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental
concept employed for constructing DNA machines and networks with a gamut of …
concept employed for constructing DNA machines and networks with a gamut of …
Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
EA Josephs, DD Kocak, CJ Fitzgibbon… - Nucleic acids …, 2015 - academic.oup.com
CRISPR-associated endonuclease Cas9 cuts DNA at variable target sites designated by a
Cas9-bound RNA molecule. Cas9's ability to be directed by single 'guide RNA'molecules to …
Cas9-bound RNA molecule. Cas9's ability to be directed by single 'guide RNA'molecules to …
Twinkle-catalyzed toehold-mediated DNA strand displacement reaction
Strand exchange between homologous nucleic acid sequences is the basis for cellular DNA
repair, recombination, and genome editing technologies. Specialized enzymes catalyze …
repair, recombination, and genome editing technologies. Specialized enzymes catalyze …
Digital-resolution detection of microRNA with single-base selectivity by photonic resonator absorption microscopy
Circulating exosomal microRNA (miR) represents a new class of blood-based biomarkers
for cancer liquid biopsy. The detection of miR at a very low concentration and with single …
for cancer liquid biopsy. The detection of miR at a very low concentration and with single …
Integrating DNA-strand-displacement circuitry with self-assembly of spherical nucleic acids
Programmable and algorithmic behaviors of DNA molecules allow one to control the
structures of DNA-assembled materials with nanometer precision and to construct complex …
structures of DNA-assembled materials with nanometer precision and to construct complex …
A universal split spinach aptamer (USSA) for nucleic acid analysis and DNA computation
N Kikuchi, DM Kolpashchikov - Chemical Communications, 2017 - pubs.rsc.org
We demonstrate how a single universal spinach aptamer (USSA) probe can be used to
detect multiple (potentially any) nucleic acid sequences. USSA can be used for cost-efficient …
detect multiple (potentially any) nucleic acid sequences. USSA can be used for cost-efficient …
Hybridization cascade plus strand-displacement isothermal amplification of RNA target with secondary structure motifs and its application for detecting dengue and …
W Saisuk, C Srisawat, S Yoksan… - Analytical chemistry, 2019 - ACS Publications
Biological RNA generally comprises secondary structure motifs which cause a problem for
target RNA detection by isothermal amplification methods. The complexity of the secondary …
target RNA detection by isothermal amplification methods. The complexity of the secondary …