Small molecules in the treatment of COVID-19
S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
Bioactive natural products in COVID-19 therapy
Z Wang, N Wang, L Yang, X Song - Frontiers in Pharmacology, 2022 - frontiersin.org
The devastating COVID-19 pandemic has caused more than six million deaths worldwide
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …
Marine natural products
Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
Cyanobacterial bioactive metabolites—A review of their chemistry and biology
Cyanobacterial blooms occur when algal densities exceed baseline population
concentrations. Cyanobacteria can produce a large number of secondary metabolites …
concentrations. Cyanobacteria can produce a large number of secondary metabolites …
Potent anti-SARS-CoV-2 activity by the natural product gallinamide A and analogues via inhibition of cathepsin L
AS Ashhurst, AH Tang, P Fajtová… - Journal of medicinal …, 2021 - ACS Publications
Cathepsin L is a key host cysteine protease utilized by coronaviruses for cell entry and is a
promising drug target for novel antivirals against SARS-CoV-2. The marine natural product …
promising drug target for novel antivirals against SARS-CoV-2. The marine natural product …
Marine pharmacology in 2014–2015: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, antiviral, and …
AMS Mayer, AJ Guerrero, AD Rodríguez… - Marine Drugs, 2019 - mdpi.com
The systematic review of the marine pharmacology literature from 2014 to 2015 was
completed in a manner consistent with the 1998–2013 reviews of this series. Research in …
completed in a manner consistent with the 1998–2013 reviews of this series. Research in …
The key role of lysosomal protease cathepsins in viral infections
M Scarcella, D d'Angelo, M Ciampa, S Tafuri… - International journal of …, 2022 - mdpi.com
Cathepsins encompass a family of lysosomal proteases that mediate protein degradation
and turnover. Although mainly localized in the endolysosomal compartment, cathepsins are …
and turnover. Although mainly localized in the endolysosomal compartment, cathepsins are …
[PDF][PDF] Natural product reports
JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …
1220 citations (792 for the period January to December 2015) referring to compounds …
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research
JB McAlpine, SN Chen, A Kutateladze… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …
community, and continuing the Raw Data Initiative, this review collects a comprehensive …
Biological targets and mechanisms of action of natural products from marine cyanobacteria
LA Salvador-Reyes, H Luesch - Natural product reports, 2015 - pubs.rsc.org
Covering: up to 2014 Marine cyanobacteria are an ancient group of organisms and prolific
producers of bioactive secondary metabolites. These compounds are presumably optimized …
producers of bioactive secondary metabolites. These compounds are presumably optimized …