Myalgia and chronic fatigue syndrome following immunization: macrophagic myofasciitis and animal studies support linkage to aluminum adjuvant persistency and …

RK Gherardi, G Crépeaux, FJ Authier - Autoimmunity Reviews, 2019 - Elsevier
Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multifactorial
and poorly undersood disabling disease. We present epidemiological, clinical and …

[HTML][HTML] Inflammation and autophagy: a convergent point between autism spectrum disorder (ASD)-related genetic and environmental factors: focus on aluminum …

L Angrand, JD Masson, A Rubio-Casillas… - Toxics, 2022 - mdpi.com
Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically
complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic …

Clearance, biodistribution, and neuromodulatory effects of aluminum-based adjuvants. Systematic review and meta-analysis: what do we learn from animal studies?

JD Masson, L Angrand, G Badran… - Critical Reviews in …, 2022 - Taylor & Francis
Aluminum (Al) salts are commonly used as adjuvants in human and veterinary vaccines for
almost a century. Despite this long history of use and the very large number of exposed …

[HTML][HTML] Multispecies evaluation of a long-acting tenofovir alafenamide subdermal implant for HIV prophylaxis

M Gunawardana, M Remedios-Chan… - Frontiers in …, 2020 - frontiersin.org
New HIV-1 infection rates far outpace the targets set by global health organizations, despite
important progress in curbing the progression of the epidemic. Long-acting (LA) formulations …

[PDF][PDF] The role of aluminum adjuvants in vaccines raises issues that deserve independent, rigorous and honest science

G Crépeaux, FJ Authier, C Exley, L Luján… - Journal of Trace …, 2020 - Elsevier
In their recent review on aluminum and vaccines [1], JP Goullé & L Grangeot-Keros
described general knowledge on aluminum (Al) exposure, kinetics and toxicity but made …

[HTML][HTML] A reactogenic “placebo” and the ethics of informed consent in Gardasil HPV vaccine clinical trials: A case study from Denmark

L Tomljenovic, LB McHenry - … Journal of Risk & Safety in …, 2024 - content.iospress.com
BACKGROUND: Medical ethics guidelines require of clinical trial investigators and sponsors
to inform prospective trial participants of all known and potential risks associated with …

Cognition and behavior in sheep repetitively inoculated with aluminum adjuvant-containing vaccines or aluminum adjuvant only

J Asín, M Pascual-Alonso, P Pinczowski… - Journal of inorganic …, 2020 - Elsevier
Sheep health management strategies often include the use of aluminum (Al)-containing
vaccines. These products were associated with the appearance of the ovine autoimmune …

Replication of small ruminant lentiviruses in aluminum hydroxide-induced granulomas in sheep: a potential new factor for viral dissemination

I Echeverría, R de Miguel, J Asín… - Journal of …, 2020 - Am Soc Microbiol
Aluminum (Al)-based salts are widely used adjuvants in ruminants and other species to
strengthen the immune response elicited against vaccine antigen (s). However, they can …

[HTML][HTML] The interaction of aluminium-based adjuvants with THP-1 macrophages in vitro: Implications for cellular survival and systemic translocation

E Shardlow, M Mold, C Exley - Journal of Inorganic Biochemistry, 2020 - Elsevier
Within clinical vaccinations, recombinant antigens are routinely entrapped inside or
adsorbed onto the surface of aluminium salts in order to increase their immunological …

Detection of aluminum in lumbar spinal cord of sheep subcutaneously inoculated with aluminum-hydroxide containing products

R de Miguel, J Asín, A Rodríguez-Largo, J Molín… - Journal of Inorganic …, 2020 - Elsevier
The use of vaccines containing aluminum (Al) adjuvants is widespread in ovine production.
Al adjuvants induce an effective immune-response but lead to the formation of post …