Molecular insights into the multifaceted functions and therapeutic targeting of high mobility group box 1 in metabolic diseases
HMGB1 is a ubiquitously expressed protein localized in nucleus, cytoplasm, as well as
secreted into extracellular space. Nuclear HMGB1 binds to DNAs and RNAs, regulating …
secreted into extracellular space. Nuclear HMGB1 binds to DNAs and RNAs, regulating …
Role of high mobility group box 1 in cardiovascular diseases
S Belmadani, K Matrougui - Inflammation, 2022 - Springer
Abstract High Mobility Group Box 1 (HMGB1) is a ubiquitous, highly conserved nuclear and
cytosolic protein that has diverse biological roles depending on its cellular location and …
cytosolic protein that has diverse biological roles depending on its cellular location and …
[HTML][HTML] Blockade of RAGE ameliorates elastase-induced emphysema development and progression via RAGE-DAMP signaling
The receptor for advanced glycan end products (RAGE) has been identified as a
susceptibility gene for chronic obstructive pulmonary disease (COPD) in genome-wide …
susceptibility gene for chronic obstructive pulmonary disease (COPD) in genome-wide …
Glycyrrhizic acid, as an inhibitor of HMGB1, alleviates bleomycin-induced pulmonary toxicity in mice through the MAPK and Smad3 pathways
Z Zhu, X Li, L He, H Cai, B Ye, Z Wu - Immunopharmacology and …, 2021 - Taylor & Francis
Aim High-mobility group box 1 (HMGB1) protein has been noticed particularly for its pivotal
role in several pathologies. However, the relevance between HMGB1 and pathological …
role in several pathologies. However, the relevance between HMGB1 and pathological …
Ferulic acid may target MyD88-mediated pro-inflammatory signaling–implications for the health protection afforded by whole grains, anthocyanins, and coffee
MF McCarty, SBI Assanga - Medical hypotheses, 2018 - Elsevier
Higher dietary intakes of anthocyanins have been linked epidemiologically to decreased risk
for metabolic syndrome, type 2 diabetes and cardiovascular events; clinical trials and rodent …
for metabolic syndrome, type 2 diabetes and cardiovascular events; clinical trials and rodent …
[HTML][HTML] A narrative review of plant and herbal medicines for delaying diabetic atherosclerosis: an update and future perspectives
ZC Wang, JO Machuki, MZ Li, KX Li… - Reviews in …, 2021 - imrpress.com
Due to their high prevalence and incidence, diabetes and atherosclerosis are increasingly
becoming global public health concerns. Atherosclerosis is one of the leading causes of …
becoming global public health concerns. Atherosclerosis is one of the leading causes of …
Clinical significance of high‐mobility group box‐1 (HMGB1) in subjects with type 2 diabetes mellitus (T2DM) combined with chronic obstructive pulmonary disease …
J Huang, T Zeng, Y Tian, Y Wu, J Yu… - Journal of clinical …, 2019 - Wiley Online Library
Background Simple method to predict type 2 diabetes mellitus (T2DM) combined with
chronic obstructive pulmonary disease (COPD) is in great need clinically. This study aims to …
chronic obstructive pulmonary disease (COPD) is in great need clinically. This study aims to …
Reduced receptor for advanced glycation end products is associated with α-SMA expression in patients with idiopathic pulmonary fibrosis and mice
H Baek, S Jang, J Park, J Jang, J Lee, SH Hong… - Laboratory Animal …, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung
disease. Despite alveolar epithelial cells is crucial role in lung, its contribution and the …
disease. Despite alveolar epithelial cells is crucial role in lung, its contribution and the …
[HTML][HTML] High levels of endothelial and platelet microvesicles in patients with type 1 diabetes irrespective of microvascular complications
K Bergen, F Mobarrez, G Jörneskog, H Wallén… - Thrombosis …, 2020 - Elsevier
Introduction Patients with type 1 diabetes have high risk of developing microvascular
complications, and microangiopathy contributes to premature cardiovascular disease in this …
complications, and microangiopathy contributes to premature cardiovascular disease in this …
Clinical significance of high mobility group box 1/toll-like receptor 4 in obese diabetic patients
S Liu, X Wang, Y Kai, C Tian, S Guo, L He, D Zhai… - Endocrine …, 2022 - jstage.jst.go.jp
High mobility group box 1 (HMGB1) is an alarmin that may link to obesity and type 2
diabetes mellitus (T2DM). The present study analyzed the correlation between HMGB1/Toll …
diabetes mellitus (T2DM). The present study analyzed the correlation between HMGB1/Toll …