Cryptococcus: from environmental saprophyte to global pathogen
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
Basic principles of the virulence of Cryptococcus
O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …
the scientific community of several reasons. This fungus is the causative agent of …
Life Cycle of Cryptococcus neoformans
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …
The 'amoeboid predator-fungal animal virulence'hypothesis
The observation that some aspects of amoeba-fungal interactions resemble animal
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …
Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
MS Fu, LC Liporagi-Lopes, SR dos Santos, JL Tenor… - MBio, 2021 - Am Soc Microbiol
Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …
microbes such as Cryptococcus neoformans; these traits can also function in animal …
Cryptococcus neoformans: Sex, morphogenesis, and virulence
Y Zhao, X Lin - Infection, Genetics and Evolution, 2021 - Elsevier
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis
mainly in immunocompromised individuals. Different morphotypes enable this …
mainly in immunocompromised individuals. Different morphotypes enable this …
Vaccination with a ZNF2oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts
Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies,
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …
Environmental triazole induces cross-resistance to clinical drugs and affects morphophysiology and virulence of Cryptococcus gattii and C. neoformans
RW Bastos, HCS Carneiro, LVN Oliveira… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause
cryptococcosis, which is usually treated with amphotericin B and fluconazole. However …
cryptococcosis, which is usually treated with amphotericin B and fluconazole. However …
Histone acetyltransferase Gcn5-mediated histone H3 acetylation facilitates cryptococcal morphogenesis and sexual reproduction
M Chen, Y Liu, Z Liu, L Su, L Yan, Y Huang, Y Huang… - Msphere, 2023 - Am Soc Microbiol
Sexual reproduction is the primary driving force behind eukaryotic environmental adaptation
and evolution. In the human fungal pathogen Cryptococcus neoformans, sexual …
and evolution. In the human fungal pathogen Cryptococcus neoformans, sexual …
Immunoprotection against cryptococcosis offered by znf2 depends on capsule and the hyphal morphology
Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the
225,000 infected people each year, even with the use of antifungal therapies. Currently …
225,000 infected people each year, even with the use of antifungal therapies. Currently …