Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …

Vaginal delivery is an important route of drug administration for both local and systemic
diseases. The vaginal route has some advantages due to its large surface area, rich blood …

Mucosa of the buccal cavity is considered a convenient and easily accessible site for the
administration of drugs intended for both local and systemic delivery. Aiming to optimize the …

The present study is concerned with the development and characterization of a novel
nanaoparticulate system; cubosomes, loaded with silver sulfadiazine (SSD), which is the …

Mucoadhesion is defined as the adherence of a synthetic or natural polymer to a mucosal
membrane via physical or chemical interactions. Mucoadhesive materials are widely used to …

Background: Hydrogels are widely used for cutaneous formulations; thereby comparing the
bioadhesive properties of polymers with a view to prolong the residence time of topical …

In this study, a pH-responsive hydrogel (cl-CMC-g-pHEA), based on carboxymethyl
cellulose/2-hydroxyethyl acrylate, was prepared. Its physicochemical properties and …

Conventional carriers for skin delivery encounter obstacles of drug leakage, scanty
permeation and low entrapment efficiency. Phospholipid nanogels have recently been …

The purpose of the present study was to develop and optimize the microemulsion based
transdermal therapeutic system for lacidipine (LCDP), a poorly water soluble and low …

The aim of the present research work was to formulate, optimize and evaluate the in-situ gel
for the ophthalmic drug delivery using the combination of gellan gum and carbopol 934P …