Synthesis, Spectroscopic Analysis, and in Vitro/in Silico Biological Studies of Novel Piperidine Derivatives Heterocyclic Schiff‐Mannich Base Compounds

S Boy, A Aras, F Türkan, O Akyıldırım… - Chemistry & …, 2021 - Wiley Online Library
In the present study, 3‐substitued‐4‐(4‐hydroxybenzylidenamino)‐4, 5‐dihydro‐1H‐1, 2, 4‐
triazol‐5‐ones (S1‐8) were synthesized by treating 4‐hydroxybenzaldehyde (B) with eight …

Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including …

S Boy, F Türkan, M Beytur, A Aras, O Akyıldırım… - Bioorganic …, 2021 - Elsevier
Abstract The synthesized Schiff Bases were reacted with formaldehyde and secondary
amine such as 2, 6-dimethylmorpholine to afford N-Mannich bases through the Mannich …

[HTML][HTML] Synthesis, Acidity and Antioxidant Properties of Some Novel 3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives

M Alkan, H Yüksek, Ö Gürsoy-Kol, M Calapoğlu - Molecules, 2008 - mdpi.com
3-Alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2, 4-triazol-5-ones 2a-g reacted with4-
diethylaminobenzaldehyde to afford the corresponding 3-alkyl (aryl)-4-(4-diethyl …

Mechanisms of the cascade synthesis of substituted 4‐amino‐1, 2, 4‐triazol‐3‐one from huisgen zwitterion and aldehyde hydrazone: A DFT study

W Zhang, Y Zhu, D Wei, M Tang - Journal of Computational …, 2012 - Wiley Online Library
The detailed reaction mechanisms of the title reaction are shed light on by using the density
functional theory (DFT). The calculated results have demonstrated that the whole reaction …

[HTML][HTML] A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones

M Alkan, H Yüksek, F İslamoğlu, Ş Bahçeci… - Molecules, 2007 - mdpi.com
Five novel 3-alkyl-4-phenylacetylamino-4, 5-dihydro-1 H-1, 2, 4-triazol-5-ones (2) were
synthesized by the reactions of 3-alkyl-4-amino-4, 5-dihydro-1 H-1, 2, 4-triazol-5-ones (1) …

Study of antioxidant properties and DNA interaction of some novel 4, 5-dihydro-1H-1, 2, 4-triazol-5-one derivatives

A Arslantas, H Yüksek, Ö Gürsoy Kol, Z Ocak… - Asian Journal of …, 2012 - hero.epa.gov
Alkyl (aryl)-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (2) reacted with 4-
benzenesulfonyloxybenzaldehyde (3) to afford the corresponding seven novel 3-alkyl (aryl) …

Cascade synthesis of substituted 4-amino-1, 2, 4-triazol-3-ones from aldehyde hydrazones and azodicarboxylates

Y Su, Z Jiang, D Hong, P Lu, Y Wang, X Lin - Tetrahedron, 2010 - Elsevier
Cascade synthesis of substituted 4-amino-1,2,4-triazol-3-ones from aldehyde hydrazones and
azodicarboxylates - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Thermodynamics-antioxidant activity relationships of some 4-benzylidenamino-4, 5-dihydro-1h-1, 2, 4-triazol-5-one derivatives: Theoretical evaluation

J Zobo Mfomo, D Bikele Mama, D Lissouck… - … Journal of Food …, 2017 - Taylor & Francis
Density functional methods were used to predict the antioxidative efficiency of thirteen 4-
benzylidenamino-4, 5-dihydro-1H-1, 2, 4-triazol-5-one derivatives in the gas phase and in …

Investigation of acidic properties of 2-ethoxy-6-(3-substitue-4, 5-dihydro-1H-1, 2, 4-triazol-5-one-4-yl-azomethine)-phenyl benzoates

H Yüksek, F Kardaş, S Manap… - Turkish Journal of …, 2021 - dergipark.org.tr
In this study, to determine the pKa values of 2-ethoxy-6-(3-substitue-4, 5-dihydro-1H-1, 2, 4-
triazol-5-one-4-yl-azomethine)-phenyl benzoates (1-9) were titrated potentiometrically with …

Synthesis, Anti-bacterial and Anti-oxidant Properties of Thiadiazaphosphol-2-ones

A Balakrishna, MVN Reddy, SK Nayak… - Chemical and …, 2008 - jstage.jst.go.jp
4-Amino-5-phenyl-4H-1, 2, 4-triazole-3-thiol (1) underwent facile condensation with various
phosphorus dichlorides (2a—j) in the presence of triethylamine in dry tetrahydrofuran at 60 …