Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Broadband coherent Raman scattering microscopy

D Polli, V Kumar, CM Valensise… - Laser & Photonics …, 2018 - Wiley Online Library
Spontaneous Raman (SR) microscopy allows label‐free chemically specific imaging based
on the vibrational response of molecules; however, due to the low Raman scattering cross …

Chemically sensitive bioimaging with coherent Raman scattering

CH Camp Jr, MT Cicerone - Nature photonics, 2015 - nature.com
Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Label-free DNA imaging in vivo with stimulated Raman scattering microscopy

FK Lu, S Basu, V Igras, MP Hoang… - Proceedings of the …, 2015 - National Acad Sciences
Label-free DNA imaging is highly desirable in biology and medicine to perform live imaging
without affecting cell function and to obtain instant histological tissue examination during …

Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy

M Ji, S Lewis, S Camelo-Piragua… - Science translational …, 2015 - science.org
Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in
brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery …

A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology

M Jermyn, J Desroches, K Aubertin… - Physics in Medicine …, 2016 - iopscience.iop.org
There is an urgent need for improved techniques for disease detection. Optical spectroscopy
and imaging technologies have potential for non-or minimally-invasive use in a wide range …

Advances in imaging plant cell walls

Y Zhao, Y Man, J Wen, Y Guo, J Lin - Trends in plant science, 2019 - cell.com
Understanding of cell wall architecture, including the crosslinking of cell wall polymers,
provides crucial information for elucidating the relationship between cell wall structure and …

Bringing vibrational imaging to chemical biology with molecular probes

J Du, H Wang, L Wei - 2022 - ACS Publications
As an emerging optical imaging modality, stimulated Raman scattering (SRS) microscopy
provides invaluable opportunities for chemical biology studies using its rich chemical …

SRS-FISH: A high-throughput platform linking microbiome metabolism to identity at the single-cell level

X Ge, FC Pereira, M Mitteregger… - Proceedings of the …, 2022 - National Acad Sciences
One of the biggest challenges in microbiome research in environmental and medical
samples is to better understand functional properties of microbial community members at a …

Quantitative stimulated Raman scattering microscopy: promises and pitfalls

B Manifold, D Fu - Annual Review of Analytical Chemistry, 2022 - annualreviews.org
Since its first demonstration, stimulated Raman scattering (SRS) microscopy has become a
powerful chemical imaging tool that shows promise in numerous biological and biomedical …