Genetic risk factors and gene–lifestyle interactions in gestational diabetes

T Jääskeläinen, MM Klemetti - Nutrients, 2022 - mdpi.com
Paralleling the increasing trends of maternal obesity, gestational diabetes (GDM) has
become a global health challenge with significant public health repercussions. In addition to …

Genetic studies of gestational diabetes and glucose metabolism in pregnancy

CE Powe, SH Kwak - Current diabetes reports, 2020 - Springer
Abstract Purpose of Review In this review, we summarize studies investigating genetics of
gestational diabetes mellitus (GDM) and glucose metabolism in pregnancy. We describe …

Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study

S Hodgson, QQ Huang, N Sallah… - PLoS …, 2022 - journals.plos.org
Background Type 2 diabetes (T2D) is highly prevalent in British South Asians, yet they are
underrepresented in research. Genes & Health (G&H) is a large, population study of British …

Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study

J Yang, F Qian, JE Chavarro, SH Ley, DK Tobias… - bmj, 2022 - bmj.com
Objectives To evaluate the individual and combined associations of five modifiable risk
factors with risk of type 2 diabetes among women with a history of gestational diabetes …

Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes

E Huvinen, J Lahti, MM Klemetti, PH Bergman… - Diabetologia, 2022 - Springer
Aims/hypothesis The aim of this study was to assess the interaction between genetic risk
and lifestyle intervention on the occurrence of gestational diabetes mellitus (GDM) and …

The prevention of gestational diabetes mellitus (The role of lifestyle): a meta-analysis

AH Altemani, RA Alzaheb - Diabetology & Metabolic Syndrome, 2022 - Springer
Gestational diabetes mellitus (GDM) is the most common complication of pregnancy. The
disease is on the rise worldwide with deleterious consequences on the fetus, mother, and …

Genetics and Epigenetics: Implications for the Life Course of Gestational Diabetes

WL Lowe Jr - International journal of molecular sciences, 2023 - mdpi.com
Gestational diabetes (GDM) is one of the most common complications of pregnancy,
affecting as many as one in six pregnancies. It is associated with both short-and long-term …

Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with …

DCH França, EL França, L Sobrevia… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Gestational diabetes mellitus is an important public health problem and has been
associated with the development of pregnancy-specific urinary incontinence. The interaction …

Risk factors for progression from gestational diabetes to postpartum type 2 diabetes: a review

AM Bengtson, SZ Ramos, DA Savitz… - Clinical obstetrics and …, 2021 - journals.lww.com
Gestational diabetes mellitus (GDM) complicates 6% to 8% of pregnancies and up to 50% of
women with GDM progress to type 2 diabetes mellitus (DM) within 5 years postpartum …

In vivo and in vitro models of diabetes: a focus on pregnancy

J Lilao-Garzón, C Valverde-Tercedor… - Diabetes: from Research …, 2021 - Springer
Diabetes in pregnancy is associated with an increased risk of poor outcomes, both for the
mother and her offspring. Although clinical and epidemiological studies are invaluable to …