Oxidative stress and assisted reproduction: a comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment

A Agarwal, I Maldonado Rosas, C Anagnostopoulou… - Antioxidants, 2022 - mdpi.com
Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

Role of oxidative stress in female reproduction

A Agarwal, S Gupta, RK Sharma - Reproductive biology and …, 2005 - Springer
In a healthy body, ROS (reactive oxygen species) and antioxidants remain in balance. When
the balance is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs …

Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings

P Guerin, S El Mouatassim… - Human reproduction …, 2001 - academic.oup.com
Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

[HTML][HTML] Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

CE Forristal, KL Wright, NA Hanley… - Reproduction …, 2010 - ncbi.nlm.nih.gov
Human embryonic stem (hES) cells are routinely cultured under atmospheric, 20% oxygen
tensions but are derived from embryos which reside in a 3–5% oxygen (hypoxic) …

Oxidative stress and redox regulation on in vitro development of mammalian embryos

M Takahashi - Journal of Reproduction and Development, 2012 - jstage.jst.go.jp
Many factors affect development of mammalian preimplantation embryos in vitro. It is well
known that in vitro development of bovine embryos is highly affected by culture condition …

Effects of oxygen concentration and antioxidants on the in vitro developmental ability, production of reactive oxygen species (ROS), and DNA fragmentation in porcine …

Y Kitagawa, K Suzuki, A Yoneda, T Watanabe - Theriogenology, 2004 - Elsevier
After in vitro maturation and fertilization of porcine oocytes, the fertilized embryos were
cultured under 5 or 20% oxygen (O2) for 7 days. In embryos cultured under 5% O2 versus …

[HTML][HTML] Human hypoblast formation is not dependent on FGF signalling

M Roode, K Blair, P Snell, K Elder, S Marchant… - Developmental …, 2012 - Elsevier
Mouse embryos segregate three different lineages during preimplantation development:
trophoblast, epiblast and hypoblast. These differentiation processes are associated with …

Oviductal secretions: will they be key factors for the future ARTs?

M Aviles, A Gutierrez-Adan, P Coy - Molecular human …, 2010 - academic.oup.com
A variety of evolutionary processes has led to the development of different organs to ensure
that internal fertilization occur successfully. Fallopian tubes are a particularly interesting …

Chemically defined media and the culture of mammalian preimplantation embryos: historical perspective and current issues

MC Summers, JD Biggers - Human reproduction update, 2003 - academic.oup.com
Considerable advances in media development for the culture of preimplantation mammalian
embryos have been made since mouse embryos were first cultured and successfully …

Embryo and its mitochondria

P May-Panloup, M Boguenet, H El Hachem, PE Bouet… - Antioxidants, 2021 - mdpi.com
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …