Metabolomics and multi-omics integration: a survey of computational methods and resources

T Eicher, G Kinnebrew, A Patt, K Spencer, K Ying, Q Ma… - Metabolites, 2020 - mdpi.com
As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

B Amos, C Aurrecoechea, M Barba… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB,
https://veupathdb. org) represents the 2019 merger of VectorBase with the EuPathDB …

Microbiome differential abundance methods produce different results across 38 datasets

JT Nearing, GM Douglas, MG Hayes… - Nature …, 2022 - nature.com
Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …

[HTML][HTML] VectorBase. org updates: bioinformatic resources for invertebrate vectors of human pathogens and related organisms

GI Giraldo-Calderón, OS Harb, SA Kelly… - Current opinion in insect …, 2022 - Elsevier
VectorBase (VectorBase. org) is part of the VEuPathDB Bioinformatics Resource Center,
providing free online access to multi-omics and population biology data, focusing on …

Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids

S Wang, R Martins, MC Sullivan, ES Friedman… - Microbiome, 2019 - Springer
Background The microbiome has been implicated in the initiation and persistence of
inflammatory bowel disease. Despite the fact that diet is one of the most potent modulators of …

Correcting for batch effects in case-control microbiome studies

SM Gibbons, C Duvallet, EJ Alm - PLoS computational biology, 2018 - journals.plos.org
High-throughput data generation platforms, like mass-spectrometry, microarrays, and
second-generation sequencing are susceptible to batch effects due to run-to-run variation in …

Remodeling of the maternal gut microbiome during pregnancy is shaped by parity

ASF Berry, MK Pierdon, AM Misic, MC Sullivan… - Microbiome, 2021 - Springer
Background The maternal microbiome has emerged as an important factor in gestational
health and outcome and is associated with risk of preterm birth and offspring morbidity …

Dysbiosis of gut microbiome is associated with rupture of cerebral aneurysms

S Kawabata, M Takagaki, H Nakamura, H Oki… - Stroke, 2022 - Am Heart Assoc
Background and Purpose: Environmental factors are important with respect to the rupture of
cerebral aneurysms. However, the relationship between the gut microbiome, an …

ToxoDB: the functional genomic resource for Toxoplasma and related organisms

OS Harb, JC Kissinger, DS Roos - Toxoplasma gondii, 2020 - Elsevier
Abstract ToxoDB (http://ToxoDB. org) is the functional genomic resource for Toxoplasma and
related organisms. ToxoDB is part of the Eukaryotic Pathogen Database resources …

Board invited review: The pig microbiota and the potential for harnessing the power of the microbiome to improve growth and health

ND Aluthge, DM Van Sambeek… - Journal of animal …, 2019 - academic.oup.com
A variety of microorganisms inhabit the gastrointestinal tract of animals including bacteria,
archaea, fungi, protozoa, and viruses. Pioneers in gut microbiology have stressed the critical …