Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and
bioactive growth factors are extensively applied in tissue engineering and regenerative …

Osteochondral defect repair in osteoarthritis (OA) remains an unsolved clinical problem due
to the lack of enough seed cells in the defect and chronic inflammation in the joint. To …

Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

The unique network structure of hydrogels enables very high levels of hydrophilicity and
biocompatibility, while at the same time exhibiting the soft physical properties associated …

Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Therapeutic glucocorticoids have been widely used in rheumatic diseases since they
became available over 60 years ago. Despite the advent of more specific biologic therapies …