Skeletal muscle mass increases during postnatal development through a process of
hypertrophy, ie enlargement of individual muscle fibers, and a similar process may be …

Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden
on individuals and society. The development of preventive and therapeutic strategies …

Analysis of skeletal muscle cross sections is an important experimental technique in muscle
biology. Many aspects of immunohistochemistry and fluorescence microscopy can now be …

The largest mammalian cells are the muscle fibers, and they have multiple nuclei to support
their large cytoplasmic volumes. During hypertrophic growth, new myonuclei are recruited …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Memory is a process in which information is encoded, stored, and retrieved. For vertebrates,
the modern view has been that it occurs only in the brain. This review describes a cellular …

Mammalian cells exhibit remarkable diversity in cell size, but the factors that regulate
establishment and maintenance of these sizes remain poorly understood. This is especially …

The skeletal muscle is an immunologically unique tissue. Leukocytes, virtually absent in
physiological conditions, are quickly recruited into the tissue upon injury and persist during …

Recent loss-of-function studies show that satellite cell depletion does not promote
sarcopenia or unloading-induced atrophy, and does not prevent regrowth. Although …

Maintenance of skeletal muscle is essential for health and survival. There are marked losses
of skeletal muscle mass as well as strength and physiological function under conditions of …