From therapeutic drug monitoring to model‐informed precision dosing for antibiotics
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
Saliva sampling: Methods and devices. An overview
FG Bellagambi, T Lomonaco, P Salvo, F Vivaldi… - TrAC Trends in …, 2020 - Elsevier
The continuous exchange of chemicals with blood and the non-invasive collection make
saliva an interesting specimen for clinical applications, from the detection of biomarkers to …
saliva an interesting specimen for clinical applications, from the detection of biomarkers to …
Toward SERS-based therapeutic drug monitoring in clinical settings: Recent developments and trends
C Liu, S Weber, R Peng, L Wu, W Zhang… - TrAC Trends in …, 2023 - Elsevier
Therapeutic drug monitoring (TDM) plays an important role in ensuring optimal drug therapy
and has become increasingly important in clinical practice. In the first part of this review …
and has become increasingly important in clinical practice. In the first part of this review …
[HTML][HTML] Model-informed precision dosing: State of the art and future perspectives
IK Minichmayr, E Dreesen, M Centanni, Z Wang… - Advanced drug delivery …, 2024 - Elsevier
Abstract Model-informed precision dosing (MIPD) stands as a significant development in
personalized medicine to tailor drug dosing to individual patient characteristics. MIPD moves …
personalized medicine to tailor drug dosing to individual patient characteristics. MIPD moves …
Integrating pharmacokinetics and pharmacodynamics in operational research to end tuberculosis
JWC Alffenaar, T Gumbo, KE Dooley… - Clinical Infectious …, 2020 - academic.oup.com
Tuberculosis (TB) elimination requires innovative approaches. The new Global Tuberculosis
Network (GTN) aims to conduct research on key unmet therapeutic and diagnostic needs in …
Network (GTN) aims to conduct research on key unmet therapeutic and diagnostic needs in …
Wireless, noninvasive therapeutic drug monitoring system for saliva measurement toward medication management of schizophrenia
As an efficient patient management tool of precision medicine, decentralized therapeutic
drug monitoring (TDM) provides new vision for therapy adherence and health management …
drug monitoring (TDM) provides new vision for therapy adherence and health management …
Alternative methods for therapeutic drug monitoring and dose adjustment of tuberculosis treatment in clinical settings: a systematic review
PS Rao, N Modi, NTT Nguyen, DH Vu, YL Xie… - Clinical …, 2023 - Springer
Abstract Background and Objective Quantifying exposure to drugs for personalized dose
adjustment is of critical importance in patients with tuberculosis who may be at risk of …
adjustment is of critical importance in patients with tuberculosis who may be at risk of …
A mobile microvolume UV/visible light spectrophotometer for the measurement of levofloxacin in saliva
JWC Alffenaar, EM Jongedijk… - Journal of …, 2021 - academic.oup.com
Introduction Therapeutic drug monitoring (TDM) for personalized dosing of fluoroquinolones
has been recommended to optimize efficacy and reduce acquired drug resistance in the …
has been recommended to optimize efficacy and reduce acquired drug resistance in the …
Evaluation of saliva as a potential alternative sampling matrix for therapeutic drug monitoring of levofloxacin in patients with multidrug-resistant tuberculosis
S Ghimire, B Maharjan, EM Jongedijk… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Saliva may be a useful alternative matrix for monitoring levofloxacin concentrations in
multidrug-resistant tuberculosis (MDR-TB) patients. The objectives of this study were (i) to …
multidrug-resistant tuberculosis (MDR-TB) patients. The objectives of this study were (i) to …
Semi-automated therapeutic drug monitoring as a pillar toward personalized medicine for tuberculosis management
Standard tuberculosis (TB) management has failed to control the growing number of drug-
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …