A change of heart: Mechanisms of cardiac adaptation to acute and chronic hypoxia

AM Williams, BD Levine… - The Journal of …, 2022 - Wiley Online Library
Over the last 100 years, high‐altitude researchers have amassed a comprehensive
understanding of the global cardiac responses to acute, prolonged and lifelong hypoxia …

The 2018 global research expedition on altitude related chronic health (Global REACH) to Cerro de Pasco, Peru: an experimental overview

MM Tymko, RL Hoiland, JC Tremblay… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Herein, a methodological overview
of our research team's (Global REACH) latest high altitude research expedition to Peru is …

[图书][B] Advanced environmental exercise physiology

SS Cheung, PN Ainslie - 2022 - books.google.com
Advanced Environmental Exercise Physiology, Second Edition, offers physiology students
and exercise science professionals a complete look at the major topics and debates in the …

[图书][B] Ward, milledge and west's high altitude medicine and physiology

AM Luks, PN Ainslie, JS Lawley, RC Roach… - 2021 - taylorfrancis.com
This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

Mechanisms underpinning sympathoexcitation in hypoxia

LL Simpson, M Stembridge… - The Journal of …, 2024 - Wiley Online Library
Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …

Population history and altitude-related adaptation in the Sherpa

S Bhandari, GL Cavalleri - Frontiers in physiology, 2019 - frontiersin.org
The first ascent of Mount Everest by Tenzing Norgay and Sir Edmund Hillary in 1953 brought
global attention to the Sherpa people and human performance at altitude. The Sherpa …

Right ventricular performance during acute hypoxic exercise

LM Forbes, TM Bull, T Lahm, T Sisson… - The Journal of …, 2024 - Wiley Online Library
Acute hypoxia increases pulmonary arterial (PA) pressures, though its effect on right
ventricular (RV) function is controversial. The objective of this study was to characterize …

Global REACH 2018: Andean highlanders, chronic mountain sickness and the integrative regulation of resting blood pressure

LL Simpson, VL Meah, AR Steele… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Does chronic mountain sickness
(CMS) alter sympathetic neural control and arterial baroreflex regulation of blood pressure in …

The influence of hemoconcentration on hypoxic pulmonary vasoconstriction in acute, prolonged, and lifelong hypoxemia

M Stembridge, RL Hoiland… - American Journal …, 2021 - journals.physiology.org
Hemoconcentration can influence hypoxic pulmonary vasoconstriction (HPV) via increased
frictional force and vasoactive signaling from erythrocytes, but whether the balance of these …

Cardiac adaptation to prolonged high altitude migration assessed by speckle tracking echocardiography

X Chen, B Liu, Y Deng, F Yang, W Wang… - Frontiers in …, 2022 - frontiersin.org
Objective Exposure to high altitudes represents physiological stress that leads to significant
changes in cardiovascular properties. However, long-term cardiovascular adaptions to high …