Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases

RA Nixon, DC Rubinsztein - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Autophagy is a lysosome-based degradative process used to recycle obsolete cellular
constituents and eliminate damaged organelles and aggregate-prone proteins. Their …

Proteostasis disruption and senescence in Alzheimer's disease pathways to neurodegeneration

R Thapa, AA Bhat, M Shahwan, H Ali, G PadmaPriya… - Brain Research, 2024 - Elsevier
Alzheimer's Disease (AD) is a progressive neurological disease associated with behavioral
abnormalities, memory loss, and cognitive impairment that cause major causes of dementia …

Mechanisms of Autophagy–Lysosome Dysfunction in Neurodegenerative Diseases

D Rubinsztein, R Nixon - 2024 - repository.cam.ac.uk
Autophagy is a lysosome-based degradative process used to recycle obsolete cellular
constituents and eliminate damaged organelles and aggregate-prone proteins. Their post …