[HTML][HTML] The pharmacology of amphetamine and methylphenidate: Relevance to the neurobiology of attention-deficit/hyperactivity disorder and other psychiatric …
SV Faraone - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
Psychostimulants, including amphetamines and methylphenidate, are first-line
pharmacotherapies for individuals with attention-deficit/hyperactivity disorder (ADHD). This …
pharmacotherapies for individuals with attention-deficit/hyperactivity disorder (ADHD). This …
[HTML][HTML] The role of fMRI in drug development
Highlights•Functional MRI continues to have the potential to play a useful role in developing
novel compounds.•But the lack of consensus on optimal techniques for acquisition and …
novel compounds.•But the lack of consensus on optimal techniques for acquisition and …
[HTML][HTML] Cerebral blood flow predicts differential neurotransmitter activity
Application of metabolic magnetic resonance imaging measures such as cerebral blood flow
in translational medicine is limited by the unknown link of observed alterations to specific …
in translational medicine is limited by the unknown link of observed alterations to specific …
Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease
Parkinson's disease (PD) is characterized by dysfunction in frontal cortical and striatal
networks that regulate action control. We investigated the pharmacological effect of …
networks that regulate action control. We investigated the pharmacological effect of …
[HTML][HTML] The effects of methylphenidate on resting-state functional connectivity of the basal nucleus of meynert, locus coeruleus, and ventral tegmental area in healthy …
Background: Methylphenidate (MPH) influences catecholaminergic signaling. Extant work
examined the effects of MPH on the neural circuits of attention and cognitive control, but few …
examined the effects of MPH on the neural circuits of attention and cognitive control, but few …
[HTML][HTML] Dopaminergic system dysfunction in recreational dexamphetamine users
Dexamphetamine (dAMPH) is a stimulant drug that is widely used recreationally as well as
for the treatment of attention-deficit hyperactivity disorder (ADHD). Although animal studies …
for the treatment of attention-deficit hyperactivity disorder (ADHD). Although animal studies …
Modeling the acute pharmacological response to selective serotonin reuptake inhibitors in human brain using simultaneous PET/MR imaging
G Gryglewski, M Klöbl, N Berroterán-Infante… - European …, 2019 - Elsevier
Pharmacological imaging of the effects of selective serotonin reuptake inhibitors (SSRI) may
aid the clarification of their mechanism of action and influence treatment of highly prevalent …
aid the clarification of their mechanism of action and influence treatment of highly prevalent …
Data collection and analysis strategies for phMRI
JB Mandeville, CH Liu, W Vanduffel, JJA Marota… - …, 2014 - Elsevier
Although functional MRI traditionally has been applied mainly to study changes in task-
induced brain function, evolving acquisition methodologies and improved knowledge of …
induced brain function, evolving acquisition methodologies and improved knowledge of …
[HTML][HTML] Anger, agency, risk and action: a neurobehavioral model with proof-of-concept in healthy young adults
Introduction Anger can engender action by individuals and groups. It is thus important to
understand anger's behavioral phenotypes and their underlying neural substrates. Here, we …
understand anger's behavioral phenotypes and their underlying neural substrates. Here, we …
[HTML][HTML] Dopaminergic modulation of regional cerebral blood flow: An arterial spin labelling study of genetic and pharmacological manipulation of COMT activity
Dopamine has direct and complex vasoactive effects on cerebral circulation. Catechol-O-
methyltransferase (COMT) regulates cortical dopamine, and its activity can be influenced …
methyltransferase (COMT) regulates cortical dopamine, and its activity can be influenced …