Lupeol is a natural triterpenoid that widely exists in edible fruits and vegetables, and
medicinal plants. In the last decade, a plethora of studies on the pharmacological activities …

The identification of neurological symptoms caused by vitamin A deficiency pointed to a
critical, early developmental role of vitamin A and its metabolite, retinoic acid (RA). The …

Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive pediatric brainstem tumor
characterized by rapid and uniform patient demise. A heterozygous point mutation of histone …

The present study examined the anticancer capabilities of Bacillus coagulans supernatant-
produced copper oxide nanoparticles (BC-CuONPs) on MCF-7 and SKBR3 cancer cells …

MicroRNA (miRNA) functions in the pathogenesis of major neurodegenerative diseases
such as Alzheimer's disease (AD) are only beginning to emerge. We have observed …

Neuroblastoma is an embryonal malignancy of the sympathetic nervous system.
Spontaneous regression and differentiation of neuroblastoma is observed in a subset of …

The modulation of kinase function has become an important goal in modern drug discovery
and chemical biology research. In cancer-targeted therapies, kinase inhibitors have been …

MicroRNAs (miRNAs) regulate target gene expression through translation repression or
mRNA degradation. These non-coding RNAs are emerging as important modulators in …

Soon after birth, the regenerative capacity of the mammalian heart is lost, cardiomyocytes
withdraw from the cell cycle and demonstrate a minimal proliferation rate. Despite improved …

In the developing vertebrate retina, progenitor cells initially proliferate but begin to produce
postmitotic neurons when neuronal differentiation occurs. However, the mechanism that …