Background The aims of this research were to provide a better understanding of the specific
evidence needs for assessment of clinical and cost-effectiveness of cell and gene therapies …

Health technology assessment (HTA) has traditionally relied on cost-effectiveness analysis
(CEA) as a cornerstone of evaluation of new therapies, assessing the clinical validity and …

Objectives Our objective was to identify patient-informed value elements that can be used to
make value assessment more patient centered. Methods Mixed methods were used …

Objective To generate a value set for the Mexican adult general population to support and
facilitate the inclusion of quality-adjusted life years (QALYs) into the health technology …

Background Hepatocellular carcinoma (HCC) is associated with significant financial burden
for patients and payers. The objective of this study was to review economic models to …

Health technology assessment (HTA) methods and processes have been criticized for not
being sufficiently 'patient centric'. For example, Perfetto [1] argued that a proposed approach …

Scale and polish (SP) and oral hygiene advice (OHA) are commonly provided in primary
care dental practice to help prevent periodontal disease. These services are widely …

Background Obstructive sleep apnea (OSA) is one of the most common chronic sleep
disorders, which can be treated by different interventions. It is known that acceptance and …

Abstract Background and Objective Formative research studies can inform stated-preference
instrument development to quantify the importance of various attributes of healthcare …

Economic theory suggests that patients as the ultimate consumers of care are an essential
component of any assessment of value in healthcare [1, 2]. Economic analysis aims to …