Historical and current adenosine receptor agonists in preclinical and clinical development

KA Jacobson, DK Tosh, S Jain, ZG Gao - Frontiers in cellular …, 2019 - frontiersin.org
Adenosine receptors (ARs) function in the body's response to conditions of pathology and
stress associated with a functional imbalance, such as in the supply and demand of …

Focusing on adenosine receptors as a potential targeted therapy in human diseases

WI Effendi, T Nagano, K Kobayashi, Y Nishimura - Cells, 2020 - mdpi.com
Adenosine is involved in a range of physiological and pathological effects through
membrane-bound receptors linked to G proteins. There are four subtypes of adenosine …

ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers

MJ Henzlova, WL Duvall, AJ Einstein, MI Travin… - Journal of Nuclear …, 2016 - Springer
LEHR Low energy high resolution LVEF Left ventricular ejection fraction MBq
Megabecquerels mCi Millicuries MPI Myocardial perfusion imaging MRI Magnetic …

Cardiac imaging in the diagnosis of coronary artery disease

A Mangla, E Oliveros, KA Williams Sr… - Current problems in …, 2017 - Elsevier
Coronary artery disease (CAD) continues to be a leading cause of morbidity and mortality
worldwide. Although invasive coronary angiography has previously been the gold standard …

Purinergic signaling in mast cell degranulation and asthma

ZG Gao, KA Jacobson - Frontiers in Pharmacology, 2017 - frontiersin.org
Mast cells are responsible for the majority of allergic conditions. It was originally thought that
almost all allergic events were mediated directly only via the high-affinity immunoglobulin E …

[HTML][HTML] Coronary physiology assessment in the catheterization laboratory

F Díez-Delhoyo, E Gutiérrez-Ibañes… - World journal of …, 2015 - ncbi.nlm.nih.gov
Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery
stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of …

Bufei Yishen Formula Restores Th17/Treg Balance and Attenuates Chronic Obstructive Pulmonary Disease via Activation of the Adenosine 2a Receptor

P Zhao, X Liu, H Dong, Y Tian, S Feng… - Frontiers in …, 2020 - frontiersin.org
Bufei Yishen formula (BYF) is a Traditional Chinese Medicine (TCM) reported to ameliorate
chronic obstructive pulmonary disease (COPD) by regulating the balance between T helper …

Serious and potentially life threatening complications of cardiac stress testing: Physiological mechanisms and management strategies

V Dilsizian, H Gewirtz, N Paivanas, AN Kitsiou… - Journal of Nuclear …, 2015 - Springer
Cardiovascular stress testing provides a highly effective resource for diagnosis, prognosis,
and assessment of therapeutic effectiveness and residual risk in the management of …

The significance of automatically measured transient ischemic dilation in identifying severe and extensive coronary artery disease in regadenoson, single-isotope …

Y Golzar, A Olusanya, N Pe, SG Dua, J Golzar… - Journal of Nuclear …, 2015 - Springer
Background The critical threshold and clinical significance of transient ischemic dilation
(TID) for regadenoson, single-isotope 99m Tc SPECT myocardial perfusion imaging (MPI) …

Safety and tolerability of regadenoson in comparison with adenosine stress cardiovascular magnetic resonance: Data from a multicentre prospective registry

JV Monmeneu Menadas, MP García Gonzalez… - … International Journal of …, 2022 - Springer
To assess the feasibility and incidence of immediate complications of stress cardiovascular
magnetic resonance (CMR) with regadenoson in comparison with adenosine in a large …