Circulating tumor cell (CTC) clusters may represent one of the key mechanisms initiating the
metastasis process. However, the series of pathophysiologic events by which CTC clusters …

Cell migration is essential for a wide range of biological processes such as embryo
morphogenesis, wound healing, regeneration, and also in pathological conditions, such as …

We present a combined report on the results of three editions of the Cell Tracking
Challenge, an ongoing initiative aimed at promoting the development and objective …

Moving cells can sense and respond to physical features of the microenvironment; however,
in vivo, the significance of tissue topography is mostly unknown. Here, we used Drosophila …

The basement membrane (BM) is a specialized extracellular matrix (ECM), which underlies
or encases developing tissues. Mechanical properties of encasing BMs have been shown to …

Collective cell migration is emerging as a major driver of embryonic development,
organogenesis, tissue homeostasis, and tumor dissemination. In contrast to individually …

Collective cell migration is the coordinated movement emerging from the interaction of at
least two cells. In multicellular organisms, collective cell migration is ubiquitous. During …

Cells measure a vast variety of signals, from their environment's stiffness to chemical
concentrations and gradients; physical principles strongly limit how accurately they can do …

Accurate segmentation and tracking of cells in microscopy image sequences is extremely
beneficial in clinical diagnostic applications and biomedical research. A continuing …

Cell migration is essential for regulating many biological processes in physiological or
pathological conditions, including embryonic development and cancer invasion. In vitro and …