[HTML][HTML] Functionalized niosomes as a smart delivery device in cancer and fungal infection

P Aparajay, A Dev - European journal of pharmaceutical sciences, 2022 - Elsevier
Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Withania somnifera (L.) Dunal: Phytochemistry, structure-activity relationship, and anticancer potential

D Tewari, V Chander, A Dhyani, S Sahu, P Gupta… - Phytomedicine, 2022 - Elsevier
Background Ayurveda is a highly recognized, well-documented, and well-accepted
traditional medicine system. This system utilizes many natural products in various forms for …

Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells

V Kumar, JK Dhanjal, P Bhargava, A Kaul… - Journal of …, 2022 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) initiated in December 2019 in Wuhan,
China and became pandemic causing high fatality and disrupted normal life calling world …

Withaferin-A—A natural anticancer agent with pleitropic mechanisms of action

IC Lee, BY Choi - International journal of molecular sciences, 2016 - mdpi.com
Cancer, being the second leading cause of mortality, exists as a formidable health
challenge. In spite of our enormous efforts, the emerging complexities in the molecular …

[HTML][HTML] Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

ARMR Amin, PA Karpowicz, TE Carey, J Arbiser… - Seminars in cancer …, 2015 - Elsevier
The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to
continue to proliferate, cancer cells must somehow uncouple themselves from the many …

Evaluating anticancer properties of Withaferin A—a potent phytochemical

M Atteeq - Frontiers in Pharmacology, 2022 - frontiersin.org
Withaferin A is a C28 steroidal lactone derived from the plant Withania somnifera, commonly
known as Ashwagandha. Withaferin A has received great attention for its anticancer …

Investigating 11 Withanosides and Withanolides by UHPLC–PDA and Mass Fragmentation Studies from Ashwagandha (Withania somnifera)

A Girme, G Saste, S Pawar, AK Balasubramaniam… - ACS …, 2020 - ACS Publications
Withania somnifera (WS), also known as ashwagandha or Indian ginseng, is known for its
pharmacological significance in neurodegenerative diseases, stress, cancer …

Natural withanolides in the treatment of chronic diseases

PT White, C Subramanian, HF Motiwala… - … and chronic diseases, 2016 - Springer
Withanolides, and in particular extracts from Withania somnifera, have been used for over
3,000 years in traditional Ayurvedic and Unani Indian medical systems as well as within …

Withaferin A: a dietary supplement with promising potential as an anti-tumor therapeutic for cancer treatment-pharmacology and mechanisms

Z Xing, A Su, L Mi, Y Zhang, T He, Y Qiu… - Drug Design …, 2023 - Taylor & Francis
Cancer, as the leading cause of death worldwide, poses a serious threat to human health,
making the development of effective tumor treatments a significant challenge. Natural …

Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides

JK Dhanjal, V Kumar, S Garg, C Subramani… - International Journal of …, 2021 - Elsevier
COVID-19 caused by SARS-CoV-2 corona virus has become a global pandemic. In the
absence of drugs and vaccine, and premises of time, efforts and cost required for their …