Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

During the early stages of human large ribosomal subunit (60 S) biogenesis, an ensemble of
assembly factors establishes and fine-tunes the essential RNA functional centers of pre-60 S …

Ribosome biogenesis is a fundamental multi-step cellular process in all domains of life that
involves the production, processing, folding, and modification of ribosomal RNAs (rRNAs) …

The coordinated integration of ribosomal RNA and protein into two functional ribosomal
subunits is safeguarded by quality control checkpoints that ensure ribosomes are correctly …

Eukaryotic ribosome biogenesis involves the synthesis of ribosomal RNA (rRNA) and its
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …

Cellular responses to environmental stress are frequently mediated by RNA-binding
proteins (RBPs). Here, we examined global RBP dynamics in Saccharomyces cerevisiae in …

Ribosomes are produced in large quantities during oogenesis and are stored in the egg.
However, the egg and early embryo are translationally repressed,,–. Here, using mass …

Protein synthesis is a cyclical process consisting of translation initiation, elongation,
termination and ribosome recycling. The release factors SBDS and EFL1—both mutated in …

While lysine methylation is well-known for regulating gene expression transcriptionally, its
implications in translation have been largely uncharted. Trimethylation at lysine 22 …