Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Cerebral cavernous malformations are acquired vascular anomalies that constitute a
common cause of central nervous system hemorrhage and stroke. The past 2 decades have …

The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

Cavernous angioma (CA) is also known as cavernoma, cavernous hemangioma, and
cerebral cavernous malformation (CCM)(National Library of Medicine Medical Subject …

Cerebral cavernous malformations (CCMs) are common neurovascular lesions caused by
loss-of-function mutations in 1 of 3 genes, including KRIT1 (CCM1), CCM2, and PDCD10 …

Abstract Cerebral Cavernous Malformation (CCM) is a cerebrovascular disease of genetic
origin affecting 0.5% of the population and characterized by abnormally enlarged and leaky …

Cerebral cavernous malformations (CCMs) form following loss of the CCM protein complex
in brain endothelial cells due to increased endothelial MEKK3 signaling and KLF2/4 …

Appropriate vascular function is essential for the maintenance of central nervous system
homeostasis and is achieved through virtue of the blood-brain barrier; a specialized …

Abstract Cerebral Cavernous Malformation (CCM) is a brain vascular disease with various
neurological symptoms. In this study, we describe the inflammatory profile in CCM and show …

Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no
currently available therapeutics. Prior evidence suggests that different cell types may play a …