Filtration methodologies for the clarification and concentration of human mesenchymal stem cells

B Cunha, C Peixoto, MM Silva, MJT Carrondo… - Journal of membrane …, 2015 - Elsevier
Currently human mesenchymal stem cells (hMSC) are expanded using microcarrier-based
stirred culture systems from one to hundreds of liters of culture volume to guarantee the …

Process development and manufacturing approaches for mesenchymal stem cell therapies

PS Couto, A Bersenev, QA Rafiq - Engineering strategies for regenerative …, 2020 - Elsevier
The emergence of cell and gene therapies (CGTs) as a novel therapeutic modality has
ushered in significant scope and opportunity to address previously unmet need. The …

[PDF][PDF] Advances in Cell-based Therapeutic Process Development

S Gretzinger - 2020 - core.ac.uk
The prospect of substituting damaged or diseased tissue by cell-based therapeutics has
created much excitement in the last decades, since cell-based therapeutics open up new …

[引用][C] Scalable Platform for the Expansion of Human Mesenchymal Stem/Stromal Cells Under Dynamic Conditions

FAG Moreira - 2018 - INSTITUTO SUPERIOR TÉCNICO