Flowing blood generates a frictional force called shear stress that has major effects on
vascular function. Branches and bends of arteries are exposed to complex blood flow …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Blood flow influences atherosclerosis by generating wall shear stress, which alters
endothelial cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a …

Responses of vascular and lymphatic endothelial cells (ECs) to fluid shear stress (FSS) from
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …

Atherosclerosis is a complex disease characterized by the formation of arterial plaques with
a broad diversity of morphological phenotypic presentations. Researchers often apply one …

High-fidelity patient-specific modeling of cardiovascular flows and hemodynamics is
challenging. Direct blood flow measurement inside the body with in-vivo measurement …

Cardiovascular diseases (CVDs), mainly ischemic heart disease (IHD) and stroke, are the
leading cause of global mortality and major contributors to disability worldwide. Despite their …

Vascular aging is accompanied by the fragmentation of elastic fibers and collagen
deposition, leading to reduced distensibility and increased vascular stiffness. A rigid artery …

Complex patterns of hemodynamic wall shear stress occur in regions of arterial branching
and curvature. Areas within these regions can be highly susceptible to atherosclerosis …