Sirtuins in atherosclerosis: guardians of healthspan and therapeutic targets
MOJ Grootaert, MR Bennett - Nature Reviews Cardiology, 2022 - nature.com
Sirtuins are NAD+-dependent deacetylase and deacylase enzymes that control important
cellular processes, including DNA damage repair, cellular metabolism, mitochondrial …
cellular processes, including DNA damage repair, cellular metabolism, mitochondrial …
[HTML][HTML] The pharmacology of resveratrol in animals and humans
EJ Park, JM Pezzuto - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2015 - Elsevier
In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …
review articles have been published. Earlier research tended to focus on pharmacological …
Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway
A Sanches-Silva, L Testai, SF Nabavi, M Battino… - Pharmacological …, 2020 - Elsevier
Cardiovascular diseases comprise of non-communicable disorders that involve the heart
and/or blood vessels and have become the leading cause of death worldwide with …
and/or blood vessels and have become the leading cause of death worldwide with …
Nutraceutical therapies for atherosclerosis
Atherosclerosis is a chronic inflammatory disease affecting large and medium arteries and is
considered to be a major underlying cause of cardiovascular disease (CVD). Although the …
considered to be a major underlying cause of cardiovascular disease (CVD). Although the …
[HTML][HTML] The roles of macrophage autophagy in atherosclerosis
B Shao, B Han, Y Zeng, D Su, C Liu - Acta Pharmacologica Sinica, 2016 - nature.com
Although various types of drugs and therapies are available to treat atherosclerosis, it
remains a major cause of mortality throughout the world. Macrophages are the major source …
remains a major cause of mortality throughout the world. Macrophages are the major source …
Targeting foam cell formation in atherosclerosis: therapeutic potential of natural products
D Wang, Y Yang, Y Lei, NT Tzvetkov, X Liu… - Pharmacological …, 2019 - ASPET
Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …
Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
[HTML][HTML] Tackling atherosclerosis via selected nutrition
A Vesnina, A Prosekov, V Atuchin, V Minina… - International journal of …, 2022 - mdpi.com
The development and pathogenesis of atherosclerosis are significantly influenced by
lifestyle, particularly nutrition. The modern level of science and technology development …
lifestyle, particularly nutrition. The modern level of science and technology development …
[HTML][HTML] A comprehensive analysis of the efficacy of resveratrol in atherosclerotic cardiovascular disease, myocardial infarction and heart failure
P Raj, SJ Thandapilly, J Wigle, S Zieroth, T Netticadan - Molecules, 2021 - mdpi.com
Atherosclerosis, myocardial infarction (MI) and heart failure (HF) are the main causes of
mortality and morbidity around the globe. New therapies are needed to better manage …
mortality and morbidity around the globe. New therapies are needed to better manage …
[HTML][HTML] Role of resveratrol in inhibiting pathological cardiac remodeling
S Fan, Y Hu, Y You, W Xue, R Chai, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease is a group of diseases with high mortality in clinic, including
hypertension, coronary heart disease, cardiomyopathy, heart valve disease, heart failure, to …
hypertension, coronary heart disease, cardiomyopathy, heart valve disease, heart failure, to …