Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

J Ravindran, S Prasad, BB Aggarwal - The AAPS journal, 2009 - Springer
Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF …

YJ Surh, KS Chun, HH Cha, SS Han, YS Keum… - Mutation Research …, 2001 - Elsevier
A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

BB Aggarwal, B Sung - Trends in pharmacological sciences, 2009 - cell.com
Curcumin (diferuloylmethane), a yellow pigment in the spice turmeric (also called curry
powder), has been used for centuries as a treatment for inflammatory diseases. Extensive …

Curcumin and cancer: an “old-age” disease with an “age-old” solution

P Anand, C Sundaram, S Jhurani, AB Kunnumakkara… - Cancer letters, 2008 - Elsevier
Cancer is primarily a disease of old age, and that life style plays a major role in the
development of most cancers is now well recognized. While plant-based formulations have …

A review of therapeutic effects of curcumin

A Noorafshan… - Current pharmaceutical …, 2013 - ingentaconnect.com
There is a growing interest in herbal medicine. Scientific studies have demonstrated the
beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived …

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

AB Kunnumakkara, P Anand, BB Aggarwal - Cancer letters, 2008 - Elsevier
Because most cancers are caused by dysregulation of as many as 500 different genes,
agents that target multiple gene products are needed for prevention and treatment of cancer …

Biological properties of curcumin-cellular and molecular mechanisms of action

B Joe, M Vijaykumar, BR Lokesh - Critical reviews in food science …, 2004 - Taylor & Francis
Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …

Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent

M López‐Lázaro - Molecular nutrition & food research, 2008 - Wiley Online Library
A growing body of research suggests that curcumin, the major active constituent of the
dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical …

[图书][B] Turmeric: the genus Curcuma

PN Ravindran, KN Babu, K Sivaraman - 2007 - taylorfrancis.com
For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain,
balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate …

Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of …

RJ Anto, A Mukhopadhyay, K Denning… - …, 2002 - academic.oup.com
Pharmacologically safe compounds that can inhibit the proliferation of tumor cells have
potential as anticancer agents. Curcumin, a diferuloylmethane, is a major active component …