Melatonin as a hormone: new physiological and clinical insights

J Cipolla-Neto, FG Amaral - Endocrine reviews, 2018 - academic.oup.com
Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Update on melatonin receptors: IUPHAR Review 20

R Jockers, P Delagrange… - British journal of …, 2016 - Wiley Online Library
Melatonin receptors are seven transmembrane‐spanning proteins belonging to the GPCR
superfamily. In mammals, two melatonin receptor subtypes exist‐MT1 and MT2‐encoded by …

Quantum dots as fluorescent probes: Synthesis, surface chemistry, energy transfer mechanisms, and applications

JD Schiffman, RG Balakrishna - Sensors and Actuators B: Chemical, 2018 - Elsevier
Luminescent semiconductor nanocrystals or quantum dots (QDs) provide exquisite electro-
optical properties that are ideal for biological sensing applications. Unlike traditional …

[HTML][HTML] Membrane melatonin receptors activated cell signaling in physiology and disease

G Nikolaev, R Robeva, R Konakchieva - International journal of molecular …, 2021 - mdpi.com
The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …

Melatonin membrane receptors in peripheral tissues: distribution and functions

RM Slominski, RJ Reiter… - Molecular and cellular …, 2012 - Elsevier
Many of melatonin's actions are mediated through interaction with the G-protein coupled
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or …

[图书][B] Melatoninergic system in the skin

AT Slominski, MA Zmijewski, C Skobowiat, B Zbytek… - 2012 - Springer
Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Melatonin—A pleiotropic, orchestrating regulator molecule

R Hardeland, DP Cardinali, V Srinivasan… - Progress in …, 2011 - Elsevier
Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

Melatonin receptors: molecular pharmacology and signalling in the context of system bias

E Cecon, A Oishi, R Jockers - British journal of pharmacology, 2018 - Wiley Online Library
Melatonin, N‐acetyl‐5‐methoxytryptamine, an evolutionally old molecule, is produced by the
pineal gland in vertebrates, and it binds with high affinity to melatonin receptors, which are …

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors

ML Dubocovich, P Delagrange, DN Krause… - Pharmacological …, 2010 - ASPET
The hormone melatonin (5-methoxy-N-acetyltryptamine) is synthesized primarily in the
pineal gland and retina, and in several peripheral tissues and organs. In the circulation, the …

[HTML][HTML] Melatonin: an inhibitor of breast cancer

SM Hill, VP Belancio, RT Dauchy… - Endocrine-related …, 2015 - erc.bioscientifica.com
The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …