Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

GS Malhi, D Bassett, P Boyce… - Australian & New …, 2015 - journals.sagepub.com
Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

A brief history of antidepressant drug development: from tricyclics to beyond ketamine

VS Pereira, VA Hiroaki-Sato - Acta neuropsychiatrica, 2018 - cambridge.org
ObjectiveAlthough monoaminergic-targeted drugs have prompted great advances in the
development of treatments for depression, the need for new options persists, since these …

Depression and anxiety.

JWG Tiller - Medical Journal of Australia, 2012 - search.ebscohost.com
The article discusses the co-occurrence of depression and anxiety disorders. Evidences
suggest that comorbid depression and anxiety disorders occur in up to 25% of general …

Combining antidepressants in acute treatment of depression: a meta-analysis of 38 studies including 4511 patients

J Henssler, T Bschor… - The Canadian Journal of …, 2016 - journals.sagepub.com
Objective: Combining antidepressants (ADs) for therapy of acute depression is frequently
employed, but randomized studies have yielded conflicting results. We conducted a …

Psychotropic medication use in people living with severe and persistent mental illness in the Australian community: a cross-sectional study

J Hu, SS McMillan, T Theodoros, JC Collins, S El-Den… - BMC psychiatry, 2022 - Springer
Background Psychotropic polypharmacy and high-dose prescribing may play a role in
therapy, however, with associated risks. The aim of this study was to describe current …

Treatment-resistant depression: critique of current approaches

C Wijeratne, P Sachdev - Australian & New Zealand Journal …, 2008 - journals.sagepub.com
The aim of the present study was to critically appraise current conceptual approaches;
demographic, neurobiological and clinical correlates; and management strategies of …

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response

JM Hennings, M Uhr, T Klengel, P Weber, B Pütz… - Translational …, 2015 - nature.com
Response to antidepressant treatment is highly variable with some patients responding
within a few weeks, whereas others have to wait for months until the onset of clinical effects …

Psychotropic polypharmacy in Australia, 2006 to 2015: a descriptive cohort study

J Brett, B Daniels, EA Karanges… - British journal of …, 2017 - Wiley Online Library
Aims To describe psychotropic polypharmacy in Australia between 2006 and 2015. Methods
We used pharmaceutical claims from a national 10% sample of people with complete …

Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies

P Solek, O Koszla, J Mytych, J Badura, Z Chelminiak… - Apoptosis, 2019 - Springer
Depression is a serious medical condition, typically treated by antidepressants.
Conventional monotherapy can be effective only in 60–80% of patients, thus modern …

A cross sectional study of psychotropic medicine use in Australia in 2018: A focus on polypharmacy

J Brett, SA Pearson, B Daniels… - British Journal of …, 2021 - Wiley Online Library
Aims To examine prescribed psychotropic medicine use on a given day in Australia (25
September 2018; World Pharmacists Day), with a focus on psychotropic polypharmacy …