To assist the transition of 3D bioprinting technology from simple lab-based tissue fabrication,
to fully functional and implantable organs, the technology must not only provide shape …

Microfluidic technology provides precise, controlled-environment, cost-effective, compact,
integrated, and high-throughput microsystems that are promising substitutes for …

Biomolecular signaling is of utmost importance in governing many biological processes
such as the patterning of the developing embryo where biomolecules regulate key cell-fate …

Serial dilution is a commonly used technique that generates a low-concentration working
sample from a high-concentration stock solution and is used to set up screening conditions …

Microfluidic live-cell microarrays show much promise as screening tools for biomedical
research because they could shed light on key biological processes such as cell signaling …

Gradients of biochemical molecules play a key role in many physiological processes such
as axon growth, tissue morphogenesis, and trans-epithelium nutrient transport, as well as in …

Abstract Organ-on-chip (OOC) devices are envisioned to replace animal models in
preclinical toxicity and efficacy testing. Although significant progress has been made …

Over the past decades, various microfluidic devices have been developed to investigate the
role of the molecular gradient in axonal development; however, there are very few devices …

Conventional manufacturing methods for polydimethylsiloxane (PDMS)-based microdevices
require multiple steps and elements that increase cost and production time. Also, these …

Cell-containing hydrogel modules as cell–hydrogel microunits for creating a physiologically
relevant 3D in vivo-like microenvironment with multiple cell types and unique extracellular …