Monitoring coherence between the macro and microcirculation in septic shock

J Bakker, C Ince - Current Opinion in Critical Care, 2020 - journals.lww.com
The improvement in macrohemodynamics during the resuscitation is not consistently
followed by subsequent changes in the microcirculation. This may result in both over …

Lactate and microcirculation as suitable targets for hemodynamic optimization in resuscitation of circulatory shock

ME Kiyatkin, J Bakker - Current opinion in critical care, 2017 - journals.lww.com
Although questions remain, a multimodal perfusion-based approach to resuscitation is
emerging with lactate and microcirculation as core measures. In this model, hyperlactemia …

UAMC-3203 or/and deferoxamine improve post-resuscitation myocardial dysfunction through suppressing ferroptosis in a rat model of cardiac arrest

T Jin, Q He, C Cheng, H Li, L Liang, G Zhang, C Su… - Shock, 2022 - journals.lww.com
Blocking ferroptosis reduces ischemia-reperfusion injury in some pathological contexts.
However, there is no evidence that ferroptosis contributes to post-resuscitation myocardial …

Lactate as a potential biomarker of sepsis in a rat cecal ligation and puncture model

X Zhai, Z Yang, G Zheng, T Yu, P Wang… - Mediators of …, 2018 - Wiley Online Library
We attempted to investigate whether blood lactate is a useful biomarker for sepsis in a rat
cecal ligation and puncture (CLP) model. Male Sprague‐Dawley rats underwent …

Resuscitation with hydroxyethyl starch maintains hemodynamic coherence in ovine hemorrhagic shock

PH Arnemann, M Hessler, T Kampmeier, L Seidel… - …, 2020 - pubs.asahq.org
Abstract Editor's Perspective What We Already Know about This Topic Both saline and
hydroxyethyl starch can be used for fluid resuscitation of hemorrhagic shock Hemodynamic …

微循环检测技术及其在急诊危重医学中的应用进展

王世伟, 郭建, 朱长清 - 临床急诊杂志, 2019 - whuhzzs.com
在急诊危重医学研究领域, 人体微循环(microcirculation) 状态对疾病的发生, 发展,
预后有着重要的意义, 而微循环检测, 动态监测和评估日益受到临床工作者的重视 …

Activation of pyruvate dehydrogenase activity by dichloroacetate improves survival and neurologic outcomes after cardiac arrest in rats

P Wang, M Chen, Z Yang, T Yu, J Zhu, L Zhou, J Lin… - Shock, 2018 - journals.lww.com
No pharmacological interventions are currently available to provide neuroprotection for
patients suffering from cardiac arrest. Dichloroacetate (DCA) is a pyruvate dehydrogenase …

Functional slit lamp biomicroscopy metrics correlate with cardiovascular risk

VC Karanam, L Tamariz, H Batawi, J Wang, A Galor - The ocular surface, 2019 - Elsevier
Purpose Our aim was to correlate cardiovascular risk factor estimation with bulbar
conjunctival blood flow metrics as measured through Functional Slit Lamp Biomicroscopy …

Effects of crystalloids and colloids on microcirculation, central venous oxygen saturation, and central venous-to-arterial carbon dioxide gap in a rabbit model of …

M Komori, Y Samejima, K Okamura, J Ichikawa… - Journal of …, 2019 - Springer
Objective The effects of hydroxyethyl starch (HES) on microcirculation, central venous
oxygen saturation (ScvO 2), and the central venous-to-arterial carbon dioxide gap (dCO 2) …

Activation of sigma-1 receptor by cutamesine attenuates neuronal apoptosis by inhibiting endoplasmic reticulum stress and mitochondrial dysfunction in a rat model of …

J Qin, P Wang, Y Li, L Yao, Y Liu, T Yu, J Lin, X Fang… - Shock, 2019 - journals.lww.com
Background: Global cerebral ischemic/reperfusion (I/R) injury after cardiac arrest (CA) is a
major cause of mortality and morbidity in survivors of resuscitation. We utilized a rat model of …