The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19

Y Xu, DJ Baylink, CS Chen, ME Reeves, J Xiao… - Journal of translational …, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …

Impact of childhood malnutrition on host defense and infection

MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Oxidative stress in malaria: potential benefits of antioxidant therapy

ARQ Gomes, N Cunha, ELP Varela… - International Journal of …, 2022 - mdpi.com
Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …

Vitamin D supplementation for preventing infections in children under five years of age

MY Yakoob, RA Salam, FR Khan… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Vitamin D is a micronutrient important for bone growth and immune function.
Deficiency can lead to rickets and has been linked to various infections, including respiratory …

Non-skeletal activities of vitamin D: from physiology to brain pathology

G Bivona, L Agnello, C Bellia, G Iacolino, C Scazzone… - Medicina, 2019 - mdpi.com
Vitamin D is a secosteroid hormone regulating the expression of almost 900 genes, and it is
involved in the regulation of calcium and phosphate metabolism, immune response, and …

The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease

AK Coussens - Photochemical & Photobiological Sciences, 2017 - pubs.rsc.org
The seasonality of infectious disease outbreaks suggests that environmental conditions
have a significant effect on disease risk. One of the major environmental factors that can …

1, 25‐Dihydroxy‐vitamin D3 regulates NK‐cell cytotoxicity, cytokine secretion, and degranulation in women with recurrent pregnancy losses

K Ota, S Dambaeva, MWI Kim, AR Han… - European journal of …, 2015 - Wiley Online Library
Vitamin D has a pivotal role in regulating immune responses by promoting Th2 immune
responses and suppressing Th1 responses. Propensities to a Th1 immune response and …

Reduction of respiratory infections in asthma patients supplemented with vitamin D is related to increased serum IL-10 and IFNγ levels and cathelicidin expression

E Ramos-Martínez, MR López-Vancell… - Cytokine, 2018 - Elsevier
Background Vitamin D is a molecule that modulates the immune response and shows anti-
inflammatory effects that are beneficial for the control of chronic diseases such as asthma …

Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer

S Sarkar, M Hewison, GP Studzinski… - Critical reviews in …, 2016 - Taylor & Francis
The discovery of vitamin D receptor (VDR) expression in immune cells has opened up a new
area of research into immunoregulation by vitamin D, a niche that is distinct from its classical …

A nanodrug coated with membrane from brain microvascular endothelial cells protects against experimental cerebral malaria

W Wei, W Cheng, W Dai, F Lu, Y Cheng, T Jiang… - Nano Letters, 2021 - ACS Publications
Human malaria is a global life-threatening infectious disease. Cerebral malaria (CM)
induced by Plasmodium falciparum parasites accounts for 90% of malaria deaths. Treating …