Blood flow in the microcirculation
TW Secomb - Annual Review of Fluid Mechanics, 2017 - annualreviews.org
The microcirculation is an extensive network of microvessels that distributes blood flow
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …
Design and operation of magnetophoretic systems at microscale: device and particle approaches
Combining both device and particle designs are the essential concepts to be considered in
magnetophoretic system development. Researcher efforts are often dedicated to only one of …
magnetophoretic system development. Researcher efforts are often dedicated to only one of …
Quantifying platelet margination in diabetic blood flow
Patients with type 2 diabetes mellitus (T2DM) develop thrombotic abnormalities strongly
associated with cardiovascular diseases. In addition to the changes of numerous …
associated with cardiovascular diseases. In addition to the changes of numerous …
Flow topology and targeted drug delivery in cardiovascular disease
Targeted drug delivery is a promising technique to direct the drug to the specific diseased
region. Nanoparticles have provided an attractive approach for this purpose. In practice, the …
region. Nanoparticles have provided an attractive approach for this purpose. In practice, the …
Theory to predict particle migration and margination in the pressure-driven channel flow of blood
QM Qi, ESG Shaqfeh - Physical review fluids, 2017 - APS
The inhomogeneous concentration distribution of erythrocytes and platelets in microchannel
flows particularly in directions normal to the mean flow plays a significant role in hemostasis …
flows particularly in directions normal to the mean flow plays a significant role in hemostasis …
Sub-cellular modeling of platelet transport in blood flow through microchannels with constriction
A Yazdani, GE Karniadakis - Soft Matter, 2016 - pubs.rsc.org
Platelet transport through arterial constrictions is one of the controlling processes influencing
their adhesive functions and the formation of thrombi. We perform high-fidelity mesoscopic …
their adhesive functions and the formation of thrombi. We perform high-fidelity mesoscopic …
Nanoparticle transport in cellular blood flow
The biotransport of the intravascular nanoparticle (NP) is influenced by both the complex
cellular flow environment and the NP characteristics. Being able to computationally simulate …
cellular flow environment and the NP characteristics. Being able to computationally simulate …
Red blood cell and platelet diffusivity and margination in the presence of cross-stream gradients in blood flows
The radial distribution of cells in blood flow inside vessels is highly non-homogeneous. This
leads to numerous important properties of blood, yet the mechanisms shaping these …
leads to numerous important properties of blood, yet the mechanisms shaping these …
The key events of thrombus formation: platelet adhesion and aggregation
Thrombus formation is a complex, dynamic and multistep process, involving biochemical
reactions, mechanical stimulation, hemodynamics, and so on. In this study, we concentrate …
reactions, mechanical stimulation, hemodynamics, and so on. In this study, we concentrate …
Nanoparticle diffusion in sheared cellular blood flow
Using a multiscale blood flow solver, the complete diffusion tensor of nanoparticles (NPs) in
sheared cellular blood flow is calculated over a wide range of shear rate and haematocrit. In …
sheared cellular blood flow is calculated over a wide range of shear rate and haematocrit. In …