Reproducibility in research into metal-organic frameworks in nanomedicine

RS Forgan - Communications Materials, 2024 - nature.com
Metal-organic frameworks (MOFs) are currently widely investigated for a number of potential
biomedicinal applications, with particular focus on nanoscale drug delivery. Nanomedicine …

Crafting porous nanoscaled architecture as a potential frontier for drug delivery

K Girigoswami, P Pallavi, A Girigoswami - Molecular Systems Design …, 2024 - pubs.rsc.org
Porous nanostructures exhibit remarkable nanoplatforms for payload delivery to diseased
cells with high loading capacity, favorable release profiles, improved hemocompatibility …

Continuous flow synthesis of PCN-222 (MOF-545) with controlled size and morphology: a sustainable approach for efficient production

A Zuliani, MC Castillejos, N Khiar - Green Chemistry, 2023 - pubs.rsc.org
Zirconium-based MOFs, such as PCN-222 (MOF-545), have gained attention due to their
regular porosity, tuneable pore size, versatile structure and exceptional thermal/chemical …

Adaptive size evolution of an MOFs-in-MOF nanovehicle for enhanced nucleus-targeted tumor chemotherapy

H Wang, T Fang, J Wang, M Zhang, X Mu, T Gao… - Nano Letters, 2024 - ACS Publications
A metal–organic frameworks (MOFs)-in-MOF nanovehicle (160 nm), which was constructed
with newly prepared ultrasmall Cu (I) Cu (II)-BTC MOFs (UCMs, 2.95 nm) loaded with …

Targeted metal–organic framework discovery goes digital: machine learning's quest from algorithms to atom arrangements

M Chafiq, A Chaouiki, YG Ko - Advanced Composites and Hybrid Materials, 2024 - Springer
The integration of metal nodes with organic linkers in structured architectures offers the
prospect of creating an extensive array of metal–organic frameworks (MOFs). Although this …

Coordination bonded stimuli-responsive drug delivery system of chemical actives with metal in pharmaceutical applications

S Kothawade, P Shende - Coordination Chemistry Reviews, 2024 - Elsevier
Stimuli-responsive drug delivery systems exhibit dynamic responses to pH, enzyme, redox,
magnetic, thermal, and light stimuli through reversible coordination bonds with metal ions …

Metal–Organic Framework‐Based Nanomaterials for Regulation of the Osteogenic Microenvironment

W Zheng, Z Meng, Z Zhu, X Wang, X Xu, Y Zhang… - Small, 2024 - Wiley Online Library
As the global population ages, bone diseases have become increasingly prevalent in
clinical settings. These conditions often involve detrimental factors such as infection …

Recent advances in nanozyme-mediated strategies for pathogen detection and control

T Ma, K Huang, N Cheng - International Journal of Molecular Sciences, 2023 - mdpi.com
Pathogen detection and control have long presented formidable challenges in the domains
of medicine and public health. This review paper underscores the potential of nanozymes as …

Present and Future of ZrO2 Nanostructure as Reservoir for Drug Loading and Release

RD Radu, D Drăgănescu - Coatings, 2023 - mdpi.com
Extensive research has been conducted on ZrO2 nanostructures due to their favorable
biocompatibility, low toxicity, and promising prospects in various biomedical applications …

Exploring the Potential of Enzyme-Immobilized MOFs: Biosensing, Biocatalysis, Targeted Drug Delivery and Cancer Therapy

O Prakash, D Verma, PC Singh - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Enzymes are indispensable in several applications including the drug industry, biosensing,
and degradation of pollutants. However, adverse conditions restrict the enzyme's utility in …