For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …

Parkinson's disease (PD) is the second most frequent age-related neurodegenerative
disorder. Sex is an important factor in the development of PD, as reflected by the fact that it is …

Objective To determine the pathologic substrates in patients with rapid eye movement
(REM) sleep behavior disorder (RBD) with or without a coexisting neurologic disorder …

Study Objectives REM sleep behavior disorder (RBD) is a parasomnia affecting 33% to 46%
of patients with Parkinson's disease (PD). The existence of a unique and specific impaired …

Background Concomitant REM sleep behaviour disorder (RBD) is commonly observed in
patients with Parkinson's disease (PD). Although the brainstem structures responsible for the …

Background Previous studies reported various symptoms of Parkinson's disease (PD)
associated with sex. Some were conflicting or confirmed in only one study. Objectives We …

Rapid eye movement sleep behavior disorder (RBD) is thought to be one of the most
frequent preceding symptoms of Parkinson's disease (PD). However, the prevalence of RBD …

Study Objectives: To evaluate the impact of sleep disorders on non-motor symptoms in
patients with Parkinson disease (PD). Design: This was a cross-sectional study. Patients …

REM sleep behavior disorder (RBD) is a parasomnia wherein a loss of REM sleep atonia
manifests as dream-enactment, often violent. Aside from its significance as a predictor of PD …

Objectives To investigate the impact of sleep disturbances on Parkinson's disease (PD)
clinical motor subtypes and disease-related disability in a multicentre setting. Methods We …