Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Optogenetics at the presynapse

BR Rost, J Wietek, O Yizhar, D Schmitz - Nature neuroscience, 2022 - nature.com
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …

Tailoring photosensitive ROS for advanced photodynamic therapy

DL Sai, J Lee, DL Nguyen, YP Kim - Experimental & molecular …, 2021 - nature.com
Photodynamic therapy (PDT) has been considered a noninvasive and cost-effective
modality for tumor treatment. However, the complexity of tumor microenvironments poses …

Photoinduced chemistry in fluorescent proteins: curse or blessing?

A Acharya, AM Bogdanov, BL Grigorenko… - Chemical …, 2017 - ACS Publications
Photoinduced reactions play an important role in the photocycle of fluorescent proteins from
the green fluorescent protein (GFP) family. Among such processes are photoisomerization …

[HTML][HTML] Towards overcoming obstacles of type II photodynamic therapy: Endogenous production of light, photosensitizer, and oxygen

L Yu, Z Liu, W Xu, K Jin, J Liu, X Zhu, Y Zhang… - … pharmaceutica Sinica B, 2024 - Elsevier
Conventional photodynamic therapy (PDT) approaches face challenges including limited
light penetration, low uptake of photosensitizers by tumors, and lack of oxygen in tumor …

A guide to genetically encoded tools for the study of H2O2

DD Smolyarova, OV Podgorny, DS Bilan… - The FEBS …, 2022 - Wiley Online Library
Cell metabolism heavily relies on the redox reactions that inevitably generate reactive
oxygen species (ROS). It is now well established that ROS fluctuations near basal levels …

No photon wasted: an efficient and selective singlet oxygen photosensitizing protein

M Westberg, M Bregnhøj, M Etzerodt… - The Journal of Physical …, 2017 - ACS Publications
Optogenetics has been, and will continue to be, a boon to mechanistic studies of cellular
processes. Genetically encodable proteins that sensitize the production of reactive oxygen …

DARPins: Promising scaffolds for theranostics

ON Shilova, SM Deyev - Acta Naturae (англоязычная версия), 2019 - cyberleninka.ru
Monoclonal antibodies are the classical basis for targeted therapy, but the development of
alternative binding proteins has made it possible to use non-immunoglobulin proteins as …

Visualized photodynamic nanomaterials activating tumor-associated immune landscape as a next-generation anticancer strategy

L Tian, X Li, L Guo, L Huang, X Wu, W Gao - Coordination Chemistry …, 2024 - Elsevier
As advances in high-resolution single-cell technology shed light on the complex
microenvironment of tumors, the focus of clinical strategies has shifted to single-cell …

Sustainable protein production through genetic engineering of cyanobacteria and use of atmospheric N2 gas

T Nawaz, L Gu, S Fahad, S Saud… - Food and Energy …, 2024 - Wiley Online Library
This review explores the potential of genetically engineering cyanobacteria with the aim of
synthesizing high‐value protein directly from atmospheric nitrogen. The article examines …