International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Rhinitis associated with asthma is distinct from rhinitis alone: the ARIA‐MeDALL hypothesis

J Bousquet, E Melén, T Haahtela, GH Koppelman… - Allergy, 2023 - Wiley Online Library
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

C Hoskinson, DLY Dai, KL Del Bel, AB Becker… - Nature …, 2023 - nature.com
Allergic diseases affect millions of people worldwide. An increase in their prevalence has
been associated with alterations in the gut microbiome, ie, the microorganisms and their …

The exposome in atopic dermatitis

N Stefanovic, C Flohr, AD Irvine - Allergy, 2020 - Wiley Online Library
Atopic dermatitis (AD) is a complex inflammatory disorder with multiple interactions between
genetic, immune and external factors. The sum of external factors that an individual is …

Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics

FM Aldakheel - International Journal of Environmental Research and …, 2021 - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …

Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization

A Cait, E Cardenas, PA Dimitriu, N Amenyogbe… - Journal of Allergy and …, 2019 - Elsevier
Background Allergic disease is the most frequent chronic health issue in children and has
been linked to early-life gut microbiome dysbiosis. Many lines of evidence suggest that …

Breastfeeding enrichment of B. longum subsp. infantis mitigates the effect of antibiotics on the microbiota and childhood asthma risk

DLY Dai, C Petersen, C Hoskinson, KL Del Bel… - Med, 2023 - cell.com
Background Early antibiotic exposure is linked to persistent disruption of the infant gut
microbiome and subsequent elevated pediatric asthma risk. Breastfeeding acts as a primary …

Impaired skin barrier and allergic sensitization in early infancy

S Wärnberg Gerdin, A Lie, A Asarnoj, MP Borres… - Allergy, 2022 - Wiley Online Library
Background Factors predicting allergic sensitization in the first 6 months of life are poorly
understood. We aimed to determine whether eczema, dry skin, and high transepidermal …

Critical features of an in vitro intestinal absorption model to study the first key aspects underlying food allergen sensitization

W Dijk, C Villa, S Benedé… - … Reviews in Food …, 2023 - Wiley Online Library
New types of protein sources will enter our diet in a near future, reinforcing the need for a
straightforward in vitro (cell‐based) screening model to test and predict the safety of these …

The role of the environment and exposome in atopic dermatitis

N Stefanovic, AD Irvine, C Flohr - Current Treatment Options in Allergy, 2021 - Springer
Purpose of review Atopic dermatitis (AD) is a chronic inflammatory skin disorder affecting up
to 20% of children and up to 5% of adults worldwide, contributing to significant disease …